^(18)F-FDG PET/CT观察原发性睾丸弥漫大B细胞淋巴瘤  

^(18)F-FDG PET/CT for observation of primary testicular diffuse large B cell lymphoma

作　　者：刘婷婷[1] 孙珂[1] 张晶晶[1] 刘保平[1] 韩星敏[1] LIU Tingting;SUN Ke;ZHANG Jingjing;LIU Baoping;HAN Xingmin(Department of Nuclear Medicine,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院核医学科,河南郑州450052

出　　处：《中国医学影像技术》2022年第3期427-430,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的观察原发性睾丸弥漫大B细胞淋巴瘤(PT-DLBCL)的^(18)F-FDG PET/CT表现及其诊断价值。方法回顾性分析5例经病理确诊的PT-DLBCL患者的术前及化学治疗前^(18)F-FDG PET/CT资料,观察其原发灶、淋巴结及结外病灶表现,并分析^(18)F-FDG PET/CT的诊断价值。结果5例PT-DLBCL中,^(18)F-FDG PET/CT示3例双侧睾丸病变、2例右侧睾丸病变;其原发灶最大标准摄取值(SUV_(max))为13.90~26.80,中位SUV_(max)为16.00。5例中,4例伴淋巴结内病变,见于腹膜后4例、盆腔3例、腹股沟及颈部各1例,其SUV_(max) 4.40~24.70,中位SUV_(max)为14.40;3例伴睾丸外结外病变,累及右侧臀部皮下组织、右上腹部皮肤及口咽各1例,病灶SUV_(max)分别为4.30、5.20及40.90。5例患者均接受全身化学治疗,1例完全缓解(CR),3例部分缓解(PR),1例疾病进展(PD)。结论^(18)F-FDG PET/CT可见PT-DLBCL病灶摄取增高,对于诊断其睾丸原发灶、淋巴结病变及结外病变均具一定价值。Objective To observe the value of ^(18)F-FDG PET/CT for diagnosis of primary testicular diffuse large B cell lymphoma(PT-DLBCL).Methods ^(18)F-FDG PET/CT data of 5 patients with PT-DLBCL before surgical operation and chemotherapy were retrospectively analyzed.The manifestations of primary lesions of PT-DLBCL,as well as lymph nodes and extranodal lesions of PT-DLBCL were observed,and the diagnostic value of ^(18)F-FDG PET/CT was analyzed.Results Among 5 cases of PT-DLBCL,^(18)F-FDG PET/CT showed bilateral testicular lesions in 3 cases and only right side testicular lesions in 2 cases.The maximum standard uptake values(SUV_(max))of primary testicular lesions were 13.90—26.80,and the median SUV_(max) was 16.00.Lymph node lesions were found in 4 cases,including retroperitoneum lesions in all 4 cases,pelvic lesions in 3 cases,and groin and neck lesions in 1 case,respectively,with SUV_(max) of 4.40—24.70 and the median SUV_(max) of 14.40.Extranodal lesions were observed in 3 cases,which involved the subcutaneous tissue of right hip,the skin of right upper abdomen and the oropharynx,respectively,and the SUV_(max) was 4.30,5.20 and 40.90,respectively.All 5 patients underwent systemic chemotherapy,then complete remission(CR)was observed in 1 case,while partial remission(PR)in 3 cases of and progression disease(PD)in 1 case.Conclusion ^(18)F-FDG PET/CT could show increased uptake of lesions of PT-DLBCL,which was of certain value for diagnosis of primary testicular lesions,lymph node lesions and extranodal lesions.

关 键 词：睾丸肿瘤 淋巴瘤 B细胞 正电子发射断层显像 体层摄像术 X线计算机 18氟脱氧葡萄糖 

分 类 号：R737.21[医药卫生—肿瘤] R817.4[医药卫生—临床医学]