不同年龄段兔结膜淋巴管的分布  

Assess on rabbit conjunctival lymphatic vessels distribution in different age groups

作　　者：武静怡 胡迭 周龙芳 苏滢 部倩雯 潘晓晶 Alex Huang Jing-Yi Wu;Die Hu;Long-Fang Zhou;Ying Su;Qian-Wen Bu;Xiao-Jing Pan;Alex Huang(Weifang Medical University,Weifang 261021,Shandong Province,China;Eye Institute of Shandong First Medical University,Qingdao Eye Hospital of Shandong First Medical University,Qingdao 266071,Shandong Province,China;State Key Laboratory Cultivation Base,Shandong Provincial Key Laboratory of Ophthalmology,Qingdao 266071,Shandong Province,China;School of Ophthalmology,Shandong First Medical University,Qingdao 266071,Shandong Province,China;Shiley Eye Institute,Hamilton Glaucoma Center,Viterbi Family Department of Ophthalmology,San Diego 92101,CA,USA;University of California,San Diego 92101,CA,USA)

机构地区：[1]潍坊医学院,中国山东省潍坊市261021 [2]山东第一医科大学附属眼科研究所山东第一医科大学附属青岛眼科医院,266071 [3]山东省眼科学重点实验室-省部级共建国家重点实验室培育基地,中国山东省青岛市266071 [4]山东第一医科大学眼科学院,中国山东省青岛市266071 [5]Shiley眼科研究所Hamilton青光眼中心Viterbi家族眼科机构,美国加利福尼亚州圣地亚哥市92101 [6]加利福尼亚大学,美国加利福尼亚州圣地亚哥市92101

出　　处：《国际眼科杂志》2022年第4期531-535,共5页International Eye Science

摘　　要：目的:探讨新西兰白兔结膜淋巴管的分布及其与年龄的关系。方法:将台盼蓝注射到兔眼四象限(鼻、上、颞、下象限)的结膜下形成含示踪剂囊泡,手术显微镜观察并录像;对含示踪剂囊泡引流的淋巴管数量进行计数,通过单因素方差分析分别检验各组各象限淋巴管数量的差异,并采用配对t检验比较不同年龄组同一象限内兔结膜淋巴管数目的差异。结果:新西兰白兔结膜中间部分分布有粗大环形淋巴管,单个收集淋巴管则主要分布在结膜周边部分。各年龄组内不同象限结膜淋巴管数量差异无统计学意义(均P>0.05),虽然与成年兔相比幼年兔结膜淋巴管分支较少,但两个年龄组之间淋巴管数量差异无统计学意义(均P>0.05)。结论:兔结膜内分布有丰富的淋巴管,不同象限和不同年龄的淋巴管数量差异无统计学意义。AIM:To investigate the distribution of conjunctival lymphatic vessels in New Zealand white rabbits and its relationship with age.METHODS:Subconjunctival trypan blue was injected in four quadrants(nasal,superior,temporal,and inferior)and recorded videos.The number of lymphatic outflow pathways arising from the blebs was counted.The difference in the number of lymphatic outflow pathways across the quadrants of each group was tested by single-factor analysis of variance.Paired t-test was used to compare the differences in the number of lymphatic outflow pathways in the same rabbit quadrants across different ages.RESULTS:In New Zealand white rabbits,thick annular lymphatic vessels were mainly distributed near the limbus part of the conjunctiva.The single collecting lymphatic vessels were primarily distributed in the peripheral parts.Although the lymphatic vessels of juvenile rabbits have fewer branches,the number of lymphatic vessels in the different quadrants was no significant difference in each group(all P>0.05)and was no difference between the two age groups(all P>0.05).CONCLUSION:The lymphatic vessels were abundant in rabbit conjunctiva.The number of lymphatic vessels in each quadrant and between two age groups had no significant difference.

关 键 词：结膜淋巴管 新西兰白兔 台盼蓝 年龄 

分 类 号：R73[医药卫生—肿瘤]