METTL9 mediated N1-histidine methylation of zinc transporters is required for tumor growth  

作　　者：Mengyue Lv Dan Cao Liwen Zhang Chi Hu Shukai Li Panrui Zhang Lianbang Zhu Xiao Yi Chaoliang Li Alin Yang Zhentao Yang Yi Zhu Kaiguang Zhang Wen Pan 

机构地区：[1]Department of Gastroenterology,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230026,China [2]Hefei National Laboratory for Physical Sciences at Microscale,the CAS Key Laboratory of Innate Immunity and Chronic Disease,School of Basic Medical Sciences,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230026,China [3]Key Laboratory of Structural Biology of Zhejiang Province,School of Life Sciences,Westlake University,Hangzhou 310024,China [4]Institute of Basic Medical Sciences,Westlake Institute for Advanced Study,Hangzhou 310024,China

出　　处：《Protein & Cell》2021年第12期965-970,共6页蛋白质与细胞（英文版）

基　　金：This work was supported by NSFC grant 81872327 Detail(to WP);“USTC Important Direction”Cultivation Project(WK3520000013)(to WP);“The Fundamental Research Funds for the Central Universities”(WK9110000065)(to DC).

摘　　要：Dear Editor,Histidine methylation has been known for many years(Searle and Westall,1951),but only a few proteins carrying such modifications have been studied(Webb et al.,2010;Al-Hadid et al.,2014;Kwiatkowski et al.,2018;Guo et al.,2019;Wilkinson et al.,2019;Kwiatkowski and Drozak,2020).

关 键 词：al. SEARLE tumor 

分 类 号：Q51[生物学—生物化学] R73[医药卫生—肿瘤]