TEP1 is a risk gene for sporadic cerebral palsy  

作　　者：Yangong Wang Yiran Xu Hongwei Li Tianxiang Tang Yimeng Qiao Ye Cheng Lingling Zhang Juan Song Yu Su Xiaoli Zhang Jun Wang Qing Shang Lili Song Chao Gao Dengna Zhu Xiaoyang Wang Changlian Zhu Qinghe Xing 

机构地区：[1]Institutes of Biomedical Sciences and Children's Hospital,Fudan University,Shanghai 201102,China [2]Henan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center,Department of Pediatrics,The 3rd Affiliated Hospital of Zhengzhou University and Institute of Neuroscience,Zhengzhou 450052,China [3]Commission Key Laboratory of Birth Defects Prevention,Henan Key Laboratory of Population Defects Prevention,Zhengzhou 450052,China [4]Institutes of Brain Science,State Key Laboratory of Medical Neurobiology and Collaborative Innovation Center for Brain Science,Fudan University,Shanghai 200032,China [5]Department of Pediatrics,Children’s Hospital of Zhengzhou University and Henan Children's Hospital,Zhengzhou 450053,China [6]Centre of Perinatal Medicine and Health,Sahlgrenska Academy,University of Gothenburg,Gothenburg 40530,Sweden [7]Department of Women's and Children's Health,Karolinska Institutet,Stockholm 17177,Sweden [8]Center for Brain Repair and Rehabilitation,Institute of Neuroscience and Physiology,Sahlgrenska Academy,University of Gothenburg,Gothenburg 40530,Sweden [9]Shanghai Center for Women and Children's Health,Shanghai 200062,China

出　　处：《Journal of Genetics and Genomics》2021年第12期1134-1138,共5页遗传学报（英文版）

基　　金：supported by the Shanghai Municipal Commission of Science and Technology Research Project(19JC1411000);the National Key Research and Development Plan for Stem Cell and Transformation Research(2017YFA0104202);the National Natural Science Foundation of China(U1604165,U1704281,81771418,31972880);the collaborative innovation center project construction for Shanghai women and children’s health(15GWZK0401);the Department of Science and Technology,Henan Province,China(171100310200);Health Department of Henan Province(SB201901055);the Swedish Research Council(2018-02667);Swedish Governmental grants to scientists working in health care(ALFGBG-717791);VINNMER-Marie Curie(VINNOVA,201504780);the Henan Medical Science and Technique Foundation(212102310221);the National Health Commission Key Laboratory of Birth Defects Prevention and Henan Key Laboratory of Population Defects Prevention(2021—03)。

摘　　要：Cerebral palsy (CP) is a nonprogressive dyskinesia syndrome caused by early brain injury,with an incidence of approximately2.0—3.5/1000 live births worldwide (Li et al.,2021;Moreno-DeLuca et al.,2021).Currently,there are more than 300,000 children aged 0—6 years diagnosed with CP in China (Liu et al.,1999;Yang et al.,2021),thus making it one of the most common debilitating diseases affecting children.

关 键 词：PALSY CHILDREN BIRTH 

分 类 号：R742.3[医药卫生—神经病学与精神病学]