大学一年级新生精神病风险综合征的早期识别及症状特征  

Early identification and symptom characteristics of psychosis risk syndrome in freshman

作　　者：张伟娟 吴洪军 刘浔雄 陈海冰 徐丽萍 ZHANG Weijuan;WU Hongjun;LIU Xunxiong;CHEN Haibing;XU Liping(The Fifth People′s Hospital of Jiujiang,Jiujiang,Jiangxi 332000,China)

机构地区：[1]九江市第五人民医院,江西九江332000

出　　处：《现代医药卫生》2022年第6期935-937,共3页Journal of Modern Medicine & Health

基　　金：江西省九江市科技局科技计划项目(201819003)。

摘　　要：目的研究大学一年级(大一)新生精神病风险综合征(PRS)的早期识别及症状特征。方法选取2019年11-12月九江学院大一新生1494例为筛查对象,以精神病前驱期问卷16条目版本(PQ-16)≥6分且通过PRS结构式访谈(SIPS)后被诊断为PRS的69例为PRS组,PQ-16<6分通过SIPS未被诊断为PRS的70例为非PRS组。比较两组PRS早期识别情况、PRS的类型及PRS的症状特征。结果PRS组新生PRS早期检出率(4.71%)高于非PRS组(0),差异有统计学意义(P<0.05);PRS组中轻微阳性症状综合征(APSS)类型67例,占比97.10%;遗传风险及功能恶化综合征(GRDS)类型2例,占比2.90%,同时具有APSS和GRDS两种类型2例,占比2.90%。PRS组精神病风险症状量表总分及各条目评分均高于非PRS组,差异有统计学意义(P<0.05)。结论大一新生群体中存在一定比例的PRS个体,早期识别尤为重要,需要社会、家庭、学校、医院的重点关注。Objective To study the early identification and symptom characteristics of psychosis risk syndrome(PRS)in freshmen.Methods A total of 1494 freshmen of Jiujiang University from November 2019 to December 2019 were selected as screening objects.A total of 69 students with 16-item version of the Psychotic Prodromal Questionnaire(PQ-16)≥6 scores and diagnosed as PRS after PRS structured interview(SIPS)were enrolled as the PRS group,and 70 students with PQ-16<6 scores and not diagnosed as PRS by SIPS were included in the non-PRS group.The two groups were compared in terms of early identification,types of PRS,and symptom characteristics of PRS.Results The early detection rate of neonatal psychosis risk syndrome in the PRS group(4.71%)was higher than that in the non-PRS group(0),the difference was statistically significant(P<0.05).In the PRS group,67 cases were Attenuated Positive Symptom Syndrome(APSS)type(97.10%),2 cases were Genetic Risk and Deterioration Syndrome(GRDS)type(2.90%)and 2 cases were APSS and GRDS type(2.90%).The total score and score for each item of psychosis risk symptom scale in the PRS group were higher than those in the non-PRS group,the differences were statistically significant(P<0.05).Conclusion There is a certain proportion of individuals with PRS in the freshman group.And early identification is particularly important,which needs to be paid close attention to by social,home,school and hospital.

关 键 词：精神病风险综合征 精神病前驱期问卷 精神病类型 大学生 早期识别 症状特征 

分 类 号：R74[医药卫生—神经病学与精神病学] R749.99[医药卫生—临床医学]