老年非小细胞肺癌患者通过胸腔镜下肺癌根治术与开胸手术对HR、MVV的对比研究  

A Comparative Study of HR and MVV in Elderly Patients with Non-small Cell Lung Cancer by Thoracoscopic Radical Lung Cancer Surgery and Thoracotomy

作　　者：赵喆 ZHAO Zhe(Department of Thoracic Surgery,Liaoyang Central Hospital,Liaoyang 111000,China)

机构地区：[1]辽阳市中心医院胸外科,辽宁辽阳111000

出　　处：《中国医药指南》2022年第9期69-71,共3页Guide of China Medicine

摘　　要：目的 探讨胸腔镜下肺癌根治术以及开胸手术对老年非小细胞肺癌的治疗效果。方法 将2014年1月至2017年1月期间接收的老年非小细胞肺癌患者240例作为本次研究数据,通过中心随机化分组模式分为研究组和对照组,每组120例。研究组行胸腔镜下肺癌根治术,对照组行开胸手术。记录两组手术前后手术指标、心肺功能指标、生活质量以及随访结果。结果 研究组手术用时短于对照组,术中出血量和术后引流量少于对照组,两组对比具有统计学意义(P<0.05);研究组和对照组的HR、MVV以及FEV1对比,组间无差异性(P>0.05),出院时研究组HR、MVV、FEV1优于对照组,组间对比存在统计学意义(P<0.05);两组三年生存率对比均无统计学意义(P>0.05);手术前,研究组和对照组的SF-36评分对比,组间无差异性(P>0.05),出院时研究组SF-36评分均高于对照组,组间对比存在统计学意义(P<0.05)。结论 胸腔镜下肺癌根治术在老年非小细胞肺癌中的治疗效果可行,心肺功能保留完整,具有推广意义。Objective To investigate the therapeutic effects of thoracoscopic radical lung cancer surgery and thoracotomy on elderly patients with non-small cell lung cancer. Methods Two hundred and forty elderly patients with non-small cell lung cancer admitted from January 2014 to January 2017 were taken as the data of this study, and were divided into study group and control group through the center’s randomized grouping mode, with 120 patients in each group. Radical thoracoscopic lung cancer surgery was performed in the study group and thoracotomy in the control group. Before and after the operation, the indexes of cardiopulmonary function and follow-up were recorded. Results The operative time of the study group was shorter than that of the control group, and the intraoperative blood loss and postoperative drainage volume were less than that of the control group. The comparison between the two groups was statistically significant(P<0.05). The comparison of HR, MVV and FEV1 between the study group and the control group showed no difierence between the two groups(P>0.05). HR, MVV and FEV1 in the study group were better than those in the control group at the time of discharge, and the comparison between the groups was statistically significant(P<0.05). There was no significant difierence in 3-year survival rate between the two groups(P>0.05). Before operation, there was no difierence in SF-36 scores between the study group and the control group(P>0.05). At discharge, the SF-36 scores of the study group were higher than those of the control group, and the comparison between the groups was statistically significant(P<0.05). Conclusion Thoracoscopic radical lung cancer in the elderly non-small cell lung cancer treatment efiect is feasible, cardiopulmonary function remains intact, has the significance of popularization.

关 键 词：胸腔镜 肺癌根治术 老年 非小细胞肺癌 

分 类 号：R734.2[医药卫生—肿瘤]