Lens thickness and associated ocular biometric factors among cataract patients in Shanghai  

作　　者：Jiaqi Meng Ling Wei Wenwen He Jiao Qi Yi Lu Xiangjia Zhu 

机构地区：[1]Eye Institute and Department of Ophthalmology,Eye&ENT Hospital,Fudan University,83 Fenyang Road,Xuhui District,Shanghai 200031,China [2]Key Laboratory of Myopia,Ministry of Health,Shanghai,China [3]Key Laboratory of Visual Impairment and Restoration,Shanghai,China [4]Key NHC key Laboratory of Myopia(Fudan University),Shanghai,China [5]Laboratory of Myopia,Chinese Academy of Medical Sciences,Shanghai,China

出　　处：《Eye and Vision》2021年第1期214-222,共9页眼视光学杂志（英文）

基　　金：The Chinese National Natural Science Foundation(grant nos.81970780,81870642,81670835,Beijing,China);the Shanghai Talent Development Fund(grant no.201604,Shanghai,China);the Outstanding Youth Medical Talents Program of Shanghai Health and Family Planning Commission(grant no.2017YQ011,Shanghai,China).

摘　　要：Background:To evaluate the distribution of lens thickness(LT)and its associations with other ocular biometric factors among cataract patients in Shanghai.Methods:Twenty-four thousand thirteen eyes from 24,013 cataract patients were retrospectively included.Ocular biometric factors including LT,central corneal thickness(CCT),anterior chamber depth(ACD),white-to-white(WTW)distance,anterior corneal curvature,and axial length(AL)were obtained using the IOLMaster700.The associations between LT and general or ocular factors were assessed.Results:The mean age was 62.5±13.6 years and 56.1%were female.The mean LT was 4.51±0.46 mm.The LT was greater in older patients(P<0.001).LT was positively correlated with CCT,while negatively correlated with ACD,WTW,and anterior corneal curvature(P<0.001).Multivariate analysis revealed that increased LT was associated with older age,male gender,thicker CCT,shallower ACD,larger WTW,and flatter anterior corneal curvature(P<0.001).LT changed with a variable behavior according to AL.In short eyes LT increased as AL increased,then decreased with longer AL in normal eyes and moderate myopic eyes,but increased again as AL increased in highly myopic eyes.Thickest LT was found in the 20.01-22mm AL group.The correlation between LT and other biometric factors remained significant when stratified by ALs.Conclusions:In a large Chinese cataractous population,we found that the thicker lens may be associated with older age,male gender,thicker CCT,shallower ACD,larger WTW,and flatter anterior corneal curvature.As AL increased,the change of LT was nonlinear,with the thickest lens seen in the 20-22mm AL group.

关 键 词：Lens thickness CATARACT Ocular biometry Axial length 

分 类 号：R779.66[医药卫生—眼科]