BI-RADS超声诊断基底细胞样型乳腺癌的临床价值  

Clinical value of ultrasound BI-RADS in diagnosis of basal-like breast carcinoma

作　　者：谢永林 李君 XIE Yonglin;LI Jun(Department of Ultrasound,Guangzhou Hospital of Integrated Traditional Chinese and Western Medicine,Guangzhou,Guangdong 510500,China)

机构地区：[1]广东省广州市中西医结合医院超声科,510500

出　　处：《重庆医学》2022年第6期1019-1023,共5页Chongqing medicine

摘　　要：目的研究BI-RADS超声在诊断基底细胞样型乳腺癌(BLBC)中的临床价值。方法回顾性分析2018年12月至2020年8月该院超声科经病理检查证实组织类型的33例BLBC(BLBC组,34个肿块)、20例非基底细胞样型三阴性乳腺癌(non-BLBC TNBC组,21个肿块)、20例非三阴性乳腺癌(non-TNBC组,20个肿块)患者临床资料,比较3组术前BI-RADS超声特征及相关病理结果,采用二分类logistic回归建立BLBC预测模型,评估BI-RADS在诊断BLBC中的临床价值。结果BLBC组与non-TNBC组坏死或黏液变及癌细胞分布情况比较,差异有统计学意义(P<0.05)。BLBC组与non-BLBC TNBC组肿块形态、方位、边缘特征比较,差异有统计学意义(P<0.05);BLBC组及non-TNBC组肿块形态、直径、边缘特征及超声弹性评分比较,差异有统计学意义(P<0.05)。多因素回归分析提示,logistic(P)=—3.121+2.345×微小分叶+0.987×肿块直径>2 cm+1.733×内部无回声。该回归模型在预测BLBC中的灵敏度为63.4%,特异度为76.5%,阳性预测值为68.9%,阴性预测值为69.4%。结论超声BI-RADS可有效用于BLBC肿块的术前诊断。Objective To investigate the clinical value of ultrasound BI-RADS in the diagnosis of basal-like breast carcinoma(BLBC).Methods The clinical data of 33 patients with BLBC(BLBC group,34 tumors),20 patients with non-BLBC TNBC triple-negative breast cancer(non-BLBC TNBC group,21 masses)and 20 patients with non-TNBC(non-TNBC group,20 masses)confirmed by pathological examination in Department of Ultrasound,Guangzhou Hospital of Integrated Traditional Chinese and Western Medicine from December 2018 to August 2020 were retrospectively analyzed.The preoperative BI-RADS characteristics and related pathological results were compared among the three groups.By binary logistic regression,the predictive model of BLBC was established to evaluate the clinical value of BI-RADS in the diagnosis of BLBC.Results The distribution of necrosis or mucus and cancer cells showed a significant difference between the BLBC group and the non-TNBC group(P<0.05).The tumor morphology,location and edge characteristics between the BLBC group non-BLBC TNBC group showed significant difference(P<0.05).The size,diameter,edge characteristics and elasticity scores between the BLBC group and the non-TNBC group were significantly different(P<0.05).Multivariate regression analysis indicated that logistic(P)=-3.121+2.345×micro-lobular sign+0.987×mass diameter>2 cm+1.733×no internal echo.The sensitivity,specificity,positive predictive value and negative predictive value of this model in the prediction of BLBC were 63.4%,76.5%,68.9%and 69.4%,respectively.Conclusion Ultrasound BI-RADS can be used effectively for preoperative diagnosis of BLBC masses.

关 键 词：基底细胞样型乳腺癌 BI-RADS 超声特征 术前诊断价值 回顾性分析 

分 类 号：R737.9[医药卫生—肿瘤]