经腹膜外腹腔镜前列腺癌根治术治疗局限性高危前列腺癌的临床研究  

Clinical study of extraperitoneal laparoscopic radical prostatectomy for localized high-risk prostate cancer

作　　者：刘春辉 李会兵 黄华[1] 盛永亮 李志军[1] 杨帮东[2] LIU Chun-hui;LI Hui-bing;HUANG Hua;SHENG Yong-liang;LI Zhi-jun;YANG Bang-dong(School of Clinical Medicine,Henan University of Science and Technology,The First Affiliated Hospital of Henan University of Science and Technology,Lunoyang,Henan 491000,China;Department of Urology,Puyang Peoples Hospital,Puyang,Henan 457000,China)

机构地区：[1]河南科技大学临床医学院河南科技大学第一附属医院,河南洛阳471000 [2]濮阳市人民医院泌尿外科,河南襥阳457000

出　　处：《医药论坛杂志》2022年第1期21-24,共4页Journal of Medical Forum

摘　　要：目的研究经腹膜外腹腔镜前列腺癌根治术(ELRP)用于局限性高危前列腺癌的临床效果。方法选取2018年10月—2020年12月河南科技大学第一附属医院收治的78例局限性高危前列腺癌患者,将采用经腹腔入路腹腔镜前列腺癌根治术(TLRP)治疗的39作为对照组,将采用经腹膜外腹腔镜前列腺癌根治术(ELRP)治疗的39例作为观察组,对比两组的临床治疗效果。结果观察组住院时间(13.81±0.46)d、导尿管留置时间(12.31±0.47)d、术后肠功能恢复时间(2.76±0.32)d、术中出血量(131.15±13.24)mL以及手术时间(155.37±22.47)min,与对照组比较均明显降低,对比差异有统计学意义(P<0.05);观察组拔管时、术后6个月的控尿率(82.05%)明显高于对照组(61.53%),有统计学意义(P<0.05);但术后1年再作对比,两组控尿率无明显差异,P>0.05;术后1年,观察组的生化复发率为15.38%,与对照组(12.82%)比较差异无统计学意义(P>0.05)。结论经腹膜外腹腔镜前列腺癌根治术用于局限性高危前列腺癌治疗疗效良好,且手术时间更短、创伤更小,术后恢复速度更快,值得在临床上推广应用。Objective To study the clinical effect of extraperitoneal laparoscopic radical prostatectomy(ELRP) for localized high-risk prostate cancer.Methods A total of 78 patients with localized high-risk prostate cancer who were admitted to Puyang People’s Hospital from October 2018 to December 2020 were selected. 39 patients who were treated with peritoneal laparoscopic radical prostatectomy(TLRP) were selected as the control group, and 39 patients who were treated with extraperitoneal laparoscopic radical prostatectomy(ELRP) were selected as the observation group. The clinical effects of the two groups were compared.Results The length of stay(13.81±0.46), indwelling time of ureter(12.31±0.47), postoperative recovery time of intestinal function(2.76±0.32), intraoperative blood loss(131.15±13.24) and operation time(155.37±22.47) in the observation group were significantly lower than those in the control group, P<0.05. The urinary control rate of the observation group at extubation and 6 months after operation was 82.05%, which was significantly higher than that of the control group(61.53%), P>0.05. However, there was no significant difference in urinary control rate between the two groups one year after operation(P<0.05). One year after operation, the biochemical recurrence rate of the observation group was 15.38%, which had no significant difference compared with 12.82% of the control group(P>0.05).Conclusion Peritoneal laparoscopic radical prostatectomy for localized high-risk prostate cancer has good efficacy, shorter operation time, less trauma and faster postoperative recovery, which is worthy of clinical application.

关 键 词：腹腔镜 前列腺癌根治术 局限性 高危型 前列腺癌 

分 类 号：R737.2[医药卫生—肿瘤]