Blue light-promoted cyclopropenizations of N-tosylhydrazones in water  

作　　者：Kaichuan Yan Hua He Jianglian Li Yi Luo Ruizhi Lai Li Guo Yong Wu 

机构地区：[1]Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Department of Medicinal Chemistry,Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology,West China School of Pharmacy,Sichuan University,Chengdu 610041,China

出　　处：《Chinese Chemical Letters》2021年第12期3984-3987,共4页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China (Nos. 81373259;81573286, 81773577;81602954)。

摘　　要：Carbene transfer reactions play an important role in the field of organic synthesis because of their ability to construct a variety of molecules. Herein, we reported on blue light-induced cyclopropenizations of N-tosylhydrazones in water, which avoids the use of expensive metal-based catalysts and toxic organic solvents. This metal-free and operationally simple methodology enable highly efficient cyclopropenizations, X-H insertion reactions, and cyclopropanation under mild reaction conditions.

关 键 词：N-Tosylhydrazone CARBENE METAL-FREE Cyclopropenization CYCLOPROPANATION 

分 类 号：O621.25[理学—有机化学]