精神分裂症患者认知功能与服药依从性的相关性  

Relationship between cognitive function and medication adherence in patients with schizophrenia

作　　者：陈兵 周永玲 朱晓丹[1] 彭丽丽[4] 陈红涛[4] 宋媛媛 刘娟[3] CHEN Bing;ZHOU Yongling;ZHU Xiaodan(School of Nursing,Ningxia Medical University,Yinchuan 750004,China)

机构地区：[1]宁夏回族自治区宁夏医科大学护理学院,银川750004 [2]宁安医院护理部 [3]宁夏医科大学基础医学院 [4]湖南中医药大学护理学院

出　　处：《国际精神病学杂志》2022年第1期35-37,44,共4页Journal Of International Psychiatry

基　　金：2019宁夏回族自治区重点研发计划项目(编号:2019BFG02023);2021年湖南省社会科学成果评审委员会课题(编号:XSP21YBC261)。

摘　　要：目的 探讨精神分裂症患者的认知功能与服药依从性的关系。方法 采用便利抽样法,选取于2020年9月~2020年12月在湖南省某医院就诊的87名精神分裂症患者进行调查,主要包括一般情况调查表、药物依从性评定量表、精神分裂症简明认知功能成套测评量表和自知力与治疗态度问卷。结果 Pearson单因素分析显示,认知测评中符号编码、伦敦塔、言语记忆、代币运动、语义流畅性及认知总分与服药依从性存在相关关系(P<0.05);多元线性回归分析结果显示符号编码是影响服药依从性的独立因素(P<0.05)。结论 注意力与执行能力可能是精神分裂症患者服药依从性的保护因素,提示我们今后可以从改善患者认知功能的角度提高其服药依从性。Objective To explore the relationship between cognitive function and medication adherence in patients with schizophrenia. Methods A survey of 87 schizophrenic outpatients in a hospital in Hunan province from September 2020 to December 2020 was conducted by convenience sampling method,which mainly included a general condition questionnaire,the Medication Adherence Rating Scale,the Brief Assessment of Cognition in Schizophrenia,and insight and treatment attitude questionnaire. Results Pearson univariate analysis showed that symbol coding,Tower of London,verbal memory,token movement,semantic fluency and total cognitive score were correlated with medication compliance(P< 0.05). Multiple linear regression analysis showed that symbol coding was an independent factor affecting medication adherence(P< 0.05). Conclusion Attention and executive ability may be protective factors affecting medication adherence of patients with schizophrenia,suggesting that we can improve patients’ medication adherence from the perspective of improving cognitive function in the future.

关 键 词：精神分裂症 认知功能 服药依从性 

分 类 号：R749.3[医药卫生—神经病学与精神病学]