运动认知风险综合征检出情况及危险因素分析  

Analysis on detection situation of motor cognitive risk syndrome and risk factor

作　　者：彭朗[1,2] 柳弘汉 蔡精灵 赵诗超 程宇航 祁正亮[1,2] 向庆伟[1,2] Peng Lang;Liu Honghan;Cai Jingling;Zhao Shichao;Cheng Yuhang;Qi Zhengliang;Xiang Qingwei(Hubei Provincial Hospital of Traditional Chinese Medicine,Wuhan 430061,China;Hubei Province Academy of Traditional Chinese Medicine,Wuhan 430074,China)

机构地区：[1]湖北省中医院,武汉430061 [2]湖北省中医药研究院,武汉430074

出　　处：《中华老年医学杂志》2022年第3期261-265,共5页Chinese Journal of Geriatrics

基　　金：湖北省卫健委指定性项目(WJ2021D004);武汉市科技局应用基础前沿项目(2020020601012244)。

摘　　要：目的研究运动认知风险综合征(MCR)的检出情况,并探讨其在不同年龄段人群中发生的可能危险因素。方法横断面研究,纳入2018年11月至2019年12月在湖北省中医院老年病科就诊的患者共计561例,采集一般情况、匹兹堡睡眠质量指数、老年抑郁量表、4 m步行测试、简易智力状态检查量表、Morse跌倒评估量表等资料。根据运动认知风险综合征诊断标准筛选出MCR患者,并对70岁以下、70岁及以上两个年龄段分别采用Logistic多元回归分析模型分析相关危险因素。结果年龄<70岁组中MCR 7例(2.9%),年龄≥70岁组中MCR 34例(10.7%)。在年龄<70岁人群中,MCR患者听力障碍抱怨的占比、GDS-15得分明显高于非MCR组;在年龄≥70岁人群中,Morse跌倒评估量表评分明显高于非运动认知风险组(P<0.05)。矫正相关混杂因素后,多因素Logistic回归分析结果显示,年龄<70岁组中,听力障碍抱怨(OR=26.394,P<0.05)与GDS-15(OR=1.385,P<0.05)为MCR发生的危险因素;年龄≥70岁组中,女性(OR=0.445,P<0.05)为MCR发生的保护性因素。结论MCR在不同的年龄段的危险因素不同,这可能提示MCR在不同年龄段中的发生原因及预测意义存在不同。Objective To investigate the detection rate of motoric cognitive risk(MCR)syndrome and explore the possible risk factors at different age groups.Methods A total of 561 patients from geriatric outpatient clinic of Hubei Provincial Hospital of Traditional Chinese Medicine from November 2018 to December 2019 were divided into two age groups under 70 years old(n=241)and 70 years old and above(n=320).The general information,Pittsburgh Sleep Quality Index,Geriatric Depression Scale-15(GDS-15),4-meter walking test,Mini-Mental State Examination and Morse Fall Scale were collected.Patients with MCR were screened out according to the MCR diagnostic criteria.Logistic multiple regression analysis was used to analyze the associated risk factors.Results 7 cases(7/241,2.9%)met the MCR diagnostic criteria in age<70 years group,and 34 cases(34/320,10.7%)in age≥70 years group.The proportion of hearing impairment complaints and GDS-15 scores of MCR patients were higher than those of the non-MCR group in age<70 years group,and the Morse Fall Scale of MCR patients was higher than that of the non-MCR group in age≥70 years old group(P<0.05).After adjusting for associated confounding factors,multiple logistic regression analysis showed that hearing impairment complaints(OR=26.394,P<0.05)and GDS-15(OR=1.385,P<0.05)were independent risk factors for MCR in age<70 years group.And female(OR=0.445,P<0.05)was a protective factor for MCR in age≥70 years old group.Conclusions Motoric cognitive risk syndrome has different risk factors in different age groups,which may indicate that the causes and predictive significance of MCR in these two different age groups are different.

关 键 词：运动认知风险综合征 痴呆 危险因素 

分 类 号：R749[医药卫生—神经病学与精神病学]