Dietary Exposure to Fumonisins and Health Risk Assessment in the Sixth China Total Diet Study——China,2015-2020  

作　　者：Shuo Zhang Shuang Zhou Bing Lyu Nannan Qiu Jingguang Li Yunfeng Zhao Yongning Wu 

机构地区：[1]NHC Key Laboratory of Food Safety Risk Assessment,Food Safety Research Unit(2019RU014)of Chinese Academy of Medical Science,China National Center for Food Safety Risk Assessment,Beijing,China

出　　处：《China CDC weekly》2021年第29期627-631,I0003,共6页中国疾病预防控制中心周报（英文）

基　　金：supported by the National Key Research and Development Program of China(2017YFC1600304 and 2017YFC1600500);the National Natural Science Foundation of China(31801456 and 31871723);Chinese Academy of Medical Science Research Unit Program(No.2019-12M-5-024).

摘　　要：Introduction:Fumonisins are a group of widespread mycotoxins mainly existing in staple foods.Their toxicological effects on humans cause worldwide public health threat.During 2015–2020,the 6th China Total Diet Study(TDS)was conducted to study the dietary exposure to fumonisins in the Chinese adult population.Methods:Fumonisins were analyzed by LCMS/MS in 288 composite dietary samples collected from 24 provincial-level administrative divisions.After combining the national consumption data with analytical results,estimated daily intakes(EDIs)were assessed and compared with health-based guide values(HBGV).Results:In the 6th China TDS,the highest fumonisin B(FBs)levels were found in staple foods/cereals among the 12 food categories.EDI of FBs was 104.9 ng/kg of body weight(bw)/day at the upper bound accounting 5.25% of the provisional maximum tolerable daily intake set by Joint Food and Agriculture Organization/World Health Organization Expert Committee on Food Additives.Among the 12 food categories,cereals and cereal products were the greatest contributor to FB exposure at 95%.Conclusion:Although the estimated exposure to FBs in the 6th China TDS were well below the HBGV for FBs in general,it was 2 times higher than the exposure in the 5th China TDS.Furthermore,the exposure to FB3 has increased remarkable and is worth further attention in China.

关 键 词：TOTAL EXPOSURE HEALTH 

分 类 号：R15[医药卫生—营养与食品卫生学]