穴位注射盐酸甲氧氯普胺联合穴位按压、敷贴预防胃癌化疗患者恶心呕吐临床研究  

Clinical Study on Point Injection with Metoclopramide Combined with Point Pressing and Application for Prevention of Nausea and Vomiting in Patients Undergoing Chemotherapy of Gastric Cancer

作　　者：叶亚萍 陈沙沙 YE Yaping;CHEN Shasha

机构地区：[1]台州市路桥区中医院针灸推拿科,浙江台州318050

出　　处：《新中医》2022年第5期164-167,共4页New Chinese Medicine

摘　　要：目的:观察穴位注射盐酸甲氧氯普胺联合穴位按压、敷贴预防胃癌化疗患者恶心呕吐的临床疗效。方法:选取180例胃癌化疗患者,按随机数字表法分为对照组和观察组各90例。对照组给予化疗和昂司丹琼治疗,观察组在对照组基础上给予穴位注射盐酸甲氧氯普胺联合穴位按压、敷贴治疗。比较2组恶心程度分级、呕吐情况、生活质量及Karnofsky功能状态(KPS)评分。结果:治疗后,观察组恶心程度分级轻于对照组,差异有统计学意义(P<0.05)。观察组呕吐缓解率为81.11%,高于对照组64.44%,差异有统计学意义(P<0.05)。治疗后,2组生活质量评分及KPS评分较治疗前升高,且观察组生活质量评分及KPS评分均高于对照组,差异有统计学意义(P<0.05)。结论:穴位注射盐酸甲氧氯普胺联合穴位按压、敷贴能明显改善胃癌化疗患者恶心呕吐情况,提高患者生活质量。Objective:To observe the clinical effect of point injection with metoclopramide combined with point pressing and application for prevention of nausea and vomiting in patients undergoing chemotherapy of gastric cancer.Methods:A total of 180 cases of patients undergoing chemotherapy of gastric cancer were selected and divided into the control group and the observation group according to the random number table method,with 90 cases in each group.The control group was given chemotherapy and ondansetron,and the observation group was additionally treated with point injection with metoclopramide combined with point pressing and application based on the treatment of the control group.The degree of nausea,vomiting,quality of life and scores of Karnofsky Performance Status(KPS)were compared between the two groups.Results:After treatment,the degree of nausea in the observation group was lower than that in the control group,the difference being significant(P<0.05).The remission rate of vomiting was 81.11%in the observation group,higher than that of64.44%in the control group,the difference being significant(P<0.05).After treatment,scores of quality of life and KPS in the two groups were increased when compared with those before treatment,and the two scores in the observation group were higher than those in the control group,the difference being significant(P<0.05).Conclusion:The therapy of point injection with metoclopramide combined with point pressing and application can significantly relieve nausea and vomiting of patients undergoing chemotherapy of gastric cancer,and improve their quality of life.

关 键 词：胃癌 化疗 恶心呕吐 穴位注射 盐酸甲氧氯普胺注射液 穴位按压 穴位敷贴 生活质量 

分 类 号：R735.2[医药卫生—肿瘤]