Peptidoglycan inhibits beigeing of adipose tissue  

作　　者：Hong Chen Lijun Sun Lu Feng Michael Mulholland Weizhen Zhang Yue Yin 

机构地区：[1]Department of Physiology and Pathophysiology,School of Basic Medical Sciences,Key Laboratory of Molecular Cardiovascular Science,Ministry of Education,Peking University,Beijing 100191,China [2]Department of Surgery,University of Michigan Medical Center,Ann Arbor,MI 48109-0346,USA

出　　处：《Acta Pharmaceutica Sinica B》2022年第2期990-993,共4页药学学报（英文版）

基　　金：supported by grants from the National Natural Science Foundation of China(81730020,81930015,and 82070592);National Institutes of Health Grant R01D K112755,1R01DK129360 and 1R01DK110273(USA)。

摘　　要：To the Editor:Obesity, an epidemic metabolic disease characterized by excessive fat accumulation, causes a significant economic burden on families and the society. The discovery of beige adipocytes has provided us with a brand new approach for the intervention of obesity^(1). Beige adipocytes increase energy expenditure and improve the balance of glucose and lipid metabolism. Reduction of beige adipocytes is a hallmark of obesity. Mechanism underlying the decrement of beigeing remains largely unknown.

关 键 词：Beige adipocytes Brown adipocytes OBESITY Metabolic inflammation 

分 类 号：R96[医药卫生—药理学]