ASSESSING WORKING MEMORY IN REAL-LIFE SITUATIONS WITH FUNCTIONAL NEAR-INFRARED SPECTROSCOPY  

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作  者:TING LI LI LI QINGMING LUO HUI GONG 

机构地区:[1]Britton Chance Center for Biomedical Photonics National Laboratory for Optoelectronics Huazhong University of Science and Technology Wuhan 430074,P.R.China

出  处:《Journal of Innovative Optical Health Sciences》2009年第4期423-430,共8页创新光学健康科学杂志(英文)

基  金:the National Nature Science Foundation of China(Grant no.30070261,60025514)and 111 project.

摘  要:Working memory is one of the most important functions in our brain,which has been widely studied with unreal-life measured technologies.A functional near-infrared spectroscopy(fNIRS)instrument with a portable and low-cost design is developed,which is capable of providing hemodynamic measurement associated with brain function in real-life situations.Using this instrument,we performed working memory studies involved in Chinese words encoding,verbal,and spatial stem recognition,which are mainly studied with other technologies.Our results show that fNIRS can well assess working memory activities,in comparison with the reported results mainly using other methodologies.Furthermore,we find that hemodynamic change in the prefrontal cortex during all working memory tasks is highly associated with subjects’behavioral data.fNIRS is shown to be a promising alternative to the current methodologies for studying or assessing functional brain activities in natural condition.

关 键 词:Functional near-infrared spectroscopy(fNIRS) working memory prefrontal cortex(PFC) oxy-hemoglobin deoxy-hemoglobin 

分 类 号:R74[医药卫生—神经病学与精神病学]

 

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