探究消化性溃疡合并上消化道出血应用泮托拉唑治疗的临床效果  

Clinical effect of pantoprazole in the treatment of peptic ulcer complicated with upper gastrointestinal bleeding

作　　者：肖灵辉 XIAO Ling-hui(Baihe Town Health Center,Shiyan 442100,China)

机构地区：[1]湖北省十堰市房县白鹤镇卫生院,442100

出　　处：《中国实用医药》2022年第7期138-140,共3页China Practical Medicine

摘　　要：目的探讨消化性溃疡合并上消化道出血应用泮托拉唑治疗的临床效果。方法76例消化性溃疡合并上消化道出血患者,以双盲法随机分为观察组与对照组,各38例。对照组采取奥美拉唑治疗,观察组采取泮托拉唑治疗。对比两组临床疗效、不良反应发生情况。结果观察组治疗总有效率97.37%高于对照组的81.58%,差异有统计学意义(P<0.05)。观察组不良反应发生率5.26%低于对照组的23.68%,差异有统计学意义(P<0.05)。结论泮托拉唑用于消化性溃疡合并上消化道出血治疗中,泮托拉唑较奥美拉唑疗效高且有效改善临床症状,减少不良反应,值得临床推广应用。Objective To discuss the clinical effect of pantoprazole in the treatment of peptic ulcer complicated with upper gastrointestinal bleeding.Methods A total of 76 patients with peptic ulcer and upper gastrointestinal bleeding were randomly divided into observation group and control group by double-blind method,with 38 cases in each group.The control group was treated with omeprazole,and the observation group was treated with pantoprazole.The clinical efficacy and occurrence of adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 97.37%,which was higher than 81.58% in the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 5.26%,which was lower than 23.68% in the control group,and the difference was statistically significant(P<0.05).Conclusion Pantoprazole can effectively improve clinical symptoms and reduce adverse reactions in the treatment of peptic ulcer complicated with upper gastrointestinal bleeding,which is worthy of clinical promotion and application.

关 键 词：泮托拉唑 消化性溃疡 上消化道出血 

分 类 号：R573.1[医药卫生—消化系统]