欧洲神经病学会/周围神经协会2021慢性炎性脱髓鞘性多发性神经根神经病指南的变化  

The changes in European Academy of Neurology/Peripheral Nerve Society guideline on diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy

作　　者：刘明生[1] 崔丽英[1] Liu Mingsheng;Cui Liying(Department of Neurology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]中国医学科学院北京协和医院神经科,北京100730

出　　处：《中华神经科杂志》2022年第3期181-186,共6页Chinese Journal of Neurology

摘　　要：欧洲神经病学会/周围神经协会对慢性炎性脱髓鞘性多发性神经根神经病(CIDP)的诊断和治疗指南进行了再次修订。新指南更加贴近临床实用,对近年的研究进展进行了更新,内容涉及CIDP的临床分型、电生理诊断标准以及免疫治疗、周围神经影像学检查、脑脊液检测和神经活组织检查在CIDP诊断中的价值,同时对抗郎飞结和结旁抗体、抗髓鞘相关糖蛋白抗体的检测也提出了建议,建议对CIDP患者常规检测M蛋白;并对目前CIDP的治疗药物选择进行了推荐。在此文中对其更新之处作一介绍。European Academy of Neurology/Peripheral Nerve Society revised the guideline on diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy(CIDP).Typical CIDP and CIDP variants were distinguished.The levels of diagnostic certainty of CIDP and possible CIDP can be defined according to the changes in motor and sensory nerve conduction studies.The utility of cerebrospinal fluid,peripheral nerve image,and nerve biopsy in diagnosis of CIDP was suggested.Serum auto-antibodies,including anti-nodal and paranodal antibodies,anti-myelin-associated glycoprotein antibodies were discussed.Monoclonal protein should be tested routinely in CIDP.Principles for treatment of CIDP were recommended.This guideline updated the development in CIDP and is more suitable for clinical practice.

关 键 词：多发性神经根性神经病 慢性感染性脱髓鞘性 指南 诊断 治疗 

分 类 号：R744.5[医药卫生—神经病学与精神病学]