EXTRAOCULAR CELLULAR PHOTOTRANSDUCTION  

作　　者：LING ZHU TIMON CHENG-YI LIU MINWU JIAN-QIN YUAN TONG-SHENG CHEN 

机构地区：[1]Laboratory of Laser Sports Medicine South China Normal University Guangzhou,GD 510006,China [2]MOE Key Laboratory of Laser Life Science South China Normal University Guangzhou,GD 510631,China

出　　处：《Journal of Innovative Optical Health Sciences》2009年第1期93-100,共8页创新光学健康科学杂志（英文）

基　　金：supported by the National Science Foundation of China(60878061,60478048,60178003,and 60278012);National Postdoctoral Foundation of China(20070420143);the Opening Project of MOE Key Laboratory of Laser Life Science,South China Normal University,Guangzhou 510631,China.

摘　　要：Photobiomodulation(PBM)is a modulation of monochromatic light or laser irradiation(LI)on biosystems.It is reviewed from the viewpoint of extraocular phototransduction in this paper.It was found that LI can induce extraocular phototransduction,and there may be an exact correspondence relationship of LI at different wavelengths and in different dose zones,and cellular signal transduction pathways.The signal transduction pathways can be classified into two types so that the Gs protein-mediated pathways belong to pathway 1,and the other pathways such as protein kinase Cs-mediated pathways and mitogen-activated protein kinase-mediated pathways belong to pathway 2.Almost all the present pathways found to mediate PBM belong to pathway 2,but there should be a pathway 1-mediated PBM.The previous studies were rather preliminary,and therefore further work should be done.

关 键 词：PHOTOTRANSDUCTION PHOTOBIOMODULATION HOMEOSTASIS 

分 类 号：TN2[电子电信—物理电子学]