维生素A与内耳听功能的相关性研究进展  

Advances in Research on Vitamin A and Inner Ear Function

作　　者：祝颖超 凡启军[2,3] 陈波蓓 ZHU Yingchao;FAN Qijun;CHEN Bobei(Department of Otorhinolaryngology,Head and Neck Surgery,Children's Hospital of Zhejiang University School of Medicine,Hangzhou 310000,China;Department of Otolaryngology,The Second Affiliated Hospital of Wenzhou Medical University,Wenzhou 325000,China;The Second School of Medicine,Wenzhou Medical University,Wenzhou 325000,China)

机构地区：[1]浙江大学医学院附属儿童医院耳鼻咽喉头颈外科,杭州310000 [2]温州医科大学附属第二医院耳鼻咽喉科,温州325000 [3]温州医科大学第二临床医学院,温州325000

出　　处：《中华耳科学杂志》2022年第2期329-333,共5页Chinese Journal of Otology

基　　金：温州市科技局项目(Y20180166)~~。

摘　　要：内耳听功能障碍是人类最常见的感觉系统障碍之一,其机制相对复杂,是耳科研究的热点与难点。维生素A是人体内必需的营养素,承担了广泛而重要的生理功能。近年来,维生素A对内耳听功能的影响逐渐得到关注。本文回顾维生素A与感音神经性聋的流行病学及临床研究的文献,总结维生素A在内耳听功能中可能的作用机制及研究进展,为进一步探索该领域提供思路。Inner ear dysfunction is one of the most common sensory system disorders in humans, with relatively complex mechanisms. It is a hotspot and an aporia of otolaryngology research. Vitamin A is an essential nutrient and has a wide range of important physiological functions. In recent years, effects of vitamin A on inner ear function have increasingly attracted attention. This article mainly reviews reports of epidemiological and clinical research on vitamin A and sensorineural hearing loss, and summarizes advances in research on possible mechanism of effects of vitamin A on inner ear function, to stimulate further exploration in this field.

关 键 词：维生素A 内耳畸形 细胞凋亡 氧化应激 

分 类 号：R764[医药卫生—耳鼻咽喉科]