Local hyperthermia combined with chemotherapy for the treatment of multiple recurrences of undifferentiated pleomorphic sarcoma:A case report  

作　　者：Yi-Ting Zhou Ruo-Yu Wang Yao Zhang Dong-Yi Li Jian Yu 

机构地区：[1]Hyperthermia Center,The Affiliated Zhongshan Hospital of Dalian University,Dalian 110006,China [2]Department of Medical Oncology,The Affiliated Zhongshan Hospital of Dalian University,Dalian 110006,China [3]Department of Bone and Soft Tissue Oncology,The Affiliated Zhongshan Hospital of Dalian University,Dalian 110006,China

出　　处：《World Journal of Clinical Cases》2022年第9期2916-2922,共7页世界临床病例杂志

摘　　要：BACKGROUND Undifferentiated pleomorphic sarcoma(UPS)is a type of soft tissue sarcoma,the histologic origin and differentiation direction of which are still unclear.There are few treatment options for UPS other than surgery.Herein we describe a patient who had multiple recurrences of UPS postoperatively,but R0 resection was achieved by local hyperthermia combined with chemotherapy,thus providing a new treatment approach for similar situations.CASE SUMMARY A 65-year-old man sought evaluation from a physician for a mass on his right back.After surgery,the pathologic diagnosis was fibrosarcoma.During the follow-up evaluations until 2021,the patient had four relapses of varying degrees.Postoperative pathology confirmed the recurrence of UPS on the right back.In March 2021,he underwent local hyperthermia combined with two cycles of chemotherapy for recurring lesions.After magnetic resonance imaging reexamination and preoperative examination,the patient chose surgery again.During the operation,the tumors were easy to excise,the amount of bleeding decreased significantly,and the pathologic evaluation confirmed that one of the specimens was an R0 excision.CONCLUSION Local hyperthermia combined with chemotherapy enables R0 resection to be achieved in patients with advanced UPS recurrence.

关 键 词：Undifferentiated pleomorphic sarcoma Local hyperthermia CHEMOTHERAPY R0 resection Case report 

分 类 号：R738.6[医药卫生—肿瘤]