阿仑膦酸钠相关药物性食管炎1例  

Alendronate-induced pill esophagitis:A case report

作　　者：王安华 郇通 范震 An-Hua Wang;Tong Xun;Zhen Fan(Zhejiang Chinese Medical University,Hangzhou 310053,Zhejiang Province,China;Department of Pathology,Affiliated Hangzhou First People’s Hospital,Zhejiang University School of Medicine,Hangzhou 310000,Zhejiang Province,China;Department of Gastroenterology,Affiliated Hangzhou First People’s Hospital,Zhejiang University School of Medicine,Hangzhou 310000,Zhejiang Province,China)

机构地区：[1]浙江中医药大学,浙江省杭州市310053 [2]浙江大学医学院附属杭州市第一人民医院病理科,浙江省杭州市310006 [3]浙江大学医学院附属杭州市第一人民医院消化内科,浙江省杭州市310006

出　　处：《世界华人消化杂志》2022年第7期336-340,共5页World Chinese Journal of Digestology

摘　　要：背景阿仑膦酸钠引起的食管炎是一种临床少见的药物性食管炎疾病,随着该药的广泛应用,食管不良反应事件有所增多,部分内镜医师对该病的认识相对不足,无法及时明确病因.病例简介本文报道了1例因胸痛就诊的患者,通过结合病史及典型内镜下表现确诊了阿仑膦酸钠相关药物性食管炎,去除病因,避免了进一步食管损伤.结论该病重在预防和及时诊断,详尽的病史、典型的内镜下表现和病理学特征有助于及早确诊.BACKGROUND Alendronate-induced esophagitis is a rare form of pill esophagitis. With the wide application of alendronate, the incidence of adverse events affecting the esophagus has increased;however, some endoscopists have a relatively insufficient understanding of the disease and cannot identify the cause in time.CASE SUMMARY A woman presented with chest pain and she was diagnosed with alendronate-associated pill esophagitis by the medical history and typical endoscopic findings, thus removing the cause and avoiding further esophageal injury.CONCLUSION Alendronate-associated pill esophagitis relies on prevention and timely diagnosis. A detailed medical history, typical endoscopic manifestations, and pathological features are helpful for early diagnosis.

关 键 词：阿仑膦酸钠 药物性食管炎 内镜 病理特征 

分 类 号：R571[医药卫生—消化系统]