Heracles Neo超快速气相电子鼻对不同产地、生长年限及采收期黄芪药材品质评价研究  

Quality evaluation of Astragali Radix from different origins,growth years and harvesting periods by Heracles Neo ultra-fast gas phase electronic nose

作　　者：余亦婷 赵乙萌 袁曦 曹丽娟 李西文[3] 陆兔林[1] 严国俊[1] YU Yi-ting;ZHAO Yi-meng;YUAN Xi;CAO Li-juan;LI Xi-wen;LU Tu-lin;YAN Guo-jun(School of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210023,China;Shengshibai Herbal Medicine Co.,Ltd.,Tianjin 300301,China;Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences,Beijing 100700,China)

机构地区：[1]南京中医药大学药学院,江苏南京210023 [2]盛实百草药业有限公司,天津300301 [3]中国中医科学院中药研究所,北京100700

出　　处：《中草药》2022年第5期1328-1337,共10页Chinese Traditional and Herbal Drugs

基　　金：国家重点研发计划资助(2019YFC1710603);国家自然科学基金项目(81773910,82074004);江苏高校“青蓝工程”项目(2020);2020年江苏省研究生科技创新计划(KYCX20_1612)。

摘　　要：目的建立以气味特征为指标的黄芪药材品质评价方法。方法采用Heracles Neo超快速气相电子鼻技术,获取黄芪药材气味色谱信息,进行主成分分析(principal component analysis,PCA)、判别因子分析(discriminant factor analysis,DFA)、聚类分析(cluster analysis,CA),对不同产地、生长年限及采收期黄芪药材进行品质评价。结果产地为山西南坪村、生长年限为4年、采收期为秋季的黄芪药材综合评分最高。结论Heracles Neo超快速气相电子鼻能够快速、准确地区分不同来源的黄芪药材,能用于黄芪的品质评价,对黄芪药材质量标志物(quality marker,Q-Marker)的确立提供参考。Objective To establish the quality evaluation method of Huangqi(Astragali Radix)based on odor characteristics.Methods Using Heracles Neo ultra-fast gas phase electronic nose to obtain odor chromatographic information of Astragali Radix,and then using principal component analysis(PCA),discrimination factor analysis(DFA)and cluster analysis(CA)to conduct quality evaluation of Astragali Radix from different origins,growth years and harvesting periods.Results Comprehensive score of Astragali Radix Nanping Village,Shanxi Province,growing for 4 years,and harvesting in autumn was the highest.Conclusion Heracles Neo ultrafast gas phase electronic nose can quickly and accurately distinguish Astragali Radix from different sources.This method could be used for quality evaluation of Astragali Radix,and referred for the establishment of quality markers(Q-Marker)of Astragali Radix.

关 键 词：黄芪 超快速气相电子鼻 生长年限 采收期 质量标志物 正己醛 

分 类 号：R286.2[医药卫生—中药学]