Preoperational diagnosis and management of breast ductal carcinoma in situ arising within fibroadenoma:Two case reports  

作　　者：Jun Wu Ke-Wang Sun Qiu-Ping Mo Ze-Ran Yang Yuan Chen Miao-Chun Zhong 

机构地区：[1]Department of Breast Surgery,Zhejiang Provincial People’s Hospital,People’s Hospital of Hangzhou Medical College,Hangzhou 310014,Zhejiang Province,China [2]Cancer Center,Zhejiang Provincial People’s Hospital,People’s Hospital of Hangzhou Medical College,Hangzhou 310014,Zhejiang Province,China [3]Department of Pathology,Zhejiang Provincial People’s Hospital

出　　处：《World Journal of Clinical Cases》2022年第11期3496-3504,共9页世界临床病例杂志

摘　　要：BACKGROUND Ductal carcinoma in situ(DCIS)arising within fibroadenoma is a type of tumor that is rarely encountered in clinic,with only about 100 cases of carcinoma arising within a fibroadenoma reported in the literature.Here,we present two cases of breast DCIS arising within a fibroadenoma and discuss their clinical and imaging findings as well as treatment.CASE SUMMARY The patients did not have cancer-related personal and family histories.Case 1(a 49-year-old woman)was diagnosed with a bilateral breast nodule in May 2018 and was followed(preoperative imaging data including ultrasound and mammography)for 3 years;she underwent an excisional biopsy to address an enlargement in nodule size.Case 2(a 37-year-old woman)was diagnosed with a left breast nodule in June 2021 and consequently received vacuum-assisted biopsy of the tumor which appeared as“irregularly shaped”and“unevenly textured”tissue on ultrasound.The pathological diagnosis was clear in both cases.Both patients underwent breast-conserving surgery and sentinel lymph node biopsy.The two cases received or planned to receive radiotherapy as well as endocrine therapy(tamoxifen).CONCLUSION Breast DCIS arising within a fibroadenoma is rare,but patients treated with radiotherapy and endocrine therapy can have good prognosis.

关 键 词：FIBROADENOMA Ductal carcinoma in situ Vacuum-assisted biopsy Excisional biopsy Case report 

分 类 号：R737.9[医药卫生—肿瘤]