Thyrotoxicosis after a massive levothyroxine ingestion: A case report  

作　　者：Fang Du Shi-Wei Liu Hua Yang Rui-Xue Duan Wen-Xia Ren 

机构地区：[1]Department of Endocrinology,Taiyuan Central Hospital of Shanxi Medical University,Taiyuan 030009,Shanxi Province,China [2]Department of Endocrinology and Metabolism,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China [3]Department of Endocrinology,Shanxi Bethune Hospital,Shanxi Academy of Medical Sciences,Taiyuan 030032,Shanxi Province,China

出　　处：《World Journal of Clinical Cases》2022年第11期3624-3629,共6页世界临床病例杂志

摘　　要：BACKGROUND The literature on thyrotoxicosis caused by excessive ingestion of exogenous thyroid hormone is limited,and most cases reported have involved pediatric clinical studies.CASE SUMMARY A 21-year-old woman initially presented with palpitation and chest tightness after an overdose of levothyroxine(10 mg).The patient transiently lost consciousness and developed atrial fibrillation during hospitalization.We used propylthiouracil to decrease the peripheral conversion of T4 to T3 and inhibit the synthesis of endogenous thyroxine,propranolol to control heart rate,hydrocortisone to correct severe thyrotoxicosis,and hemoperfusion to increase levothyroxine clearance.The patient recovered and was discharged.CONCLUSION For patients with thyrotoxicosis after taking excess levothyroxine,it is critical to monitor vital signs and initiate effective treatment.

关 键 词：LEVOTHYROXINE OVERDOSE THYROTOXICOSIS Thyroid crisis Treatment Case report 

分 类 号：R969[医药卫生—药理学]