眼睑热敷、睑板腺按摩联合典必殊眼膏治疗睑板腺功能障碍性干眼症的疗效观察  

Effect of Eyelid Hot Compress,Meibomian Gland Massage Combined with Tobradex Ointment in the Treatment of Dry Eye Caused by Meibomian Gland Dysfunction

作　　者：吴葛玮[1] 周馨洁 李利艳 宋婷婷 WU Ge-wei;ZHOU Xin-jie;LI Li-yan;SONG Ting-ting(Department of Ophthalmology,Beijing Shijingshan Hospital,Beijing 100043,China)

机构地区：[1]北京市石景山医院眼科,北京100043

出　　处：《医学信息》2022年第8期121-123,共3页Journal of Medical Information

摘　　要：目的研究眼睑热敷、睑板腺按摩联合典必殊眼膏治疗睑板腺功能障碍性干眼症的疗效。方法选取2020年5月-2021年5月在我院诊治的68例睑板腺功能障碍性干眼症患者为研究对象,采用随机数字表法分为对照组和观察组,各34例。对照组采用眼睑热敷、睑板腺按摩治疗,观察组在对照组基础上联合典必殊眼膏治疗,比较两组临床疗效、干眼症表现消失时间、泪液总分泌量、泪膜破裂时间、临床症状评分以及临床不良反应发生情况。结果观察组治疗总有效率为94.11%,高于对照组的82.35%,差异有统计学意义(P<0.05);观察组干眼症表现消失时间、泪膜破裂时间均短于对照组,泪液总分泌量大于对照组,差异有统计学意义(P<0.05);观察组眼干涩、眼红、眼部烧灼感、异物感、视物模糊各症状评分均低于对照组,差异有统计学意义(P<0.05);观察组临床不良反应发生率为8.82%,低于对照组的11.76%,差异无统计学意义(P>0.05)。结论眼睑热敷、睑板腺按摩联合典必殊眼膏治疗睑板腺功能障碍性干眼症效果确切,可提高治疗总有效率,在短时间内减轻临床症状,增加泪液分泌量,延迟泪膜破裂时间,且不会增加临床不良反应。Objective To study the effect of eyelid hot compress,meibomian gland massage combined with tobradex ointment in the treatment of dry eye caused by meibomian gland dysfunction.Methods A total of 68 patients with dry eye caused by meibomian gland dysfunction treated in our hospital from May 2020 to May 2021 were selected and randomly divided into control group and observation group,with 34 cases in each group.The control group was treated with eyelid hot compress and meibomian gland massage,and the observation group was treated with tobradex ointment on the basis of the control group.The clinical efficacy,disappearance time of dry eye symptoms,total tear secretion,tear film rupture time,clinical symptom score and incidence of clinical adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 94.11%,which was higher than 82.35%of the control group,and the difference was statistically significant(P<0.05).The disappearance time of dry eye symptoms and tear film rupture time in the observation group were shorter than those in the control group,and the total tear secretion was greater than that in the control group,the difference was statistically significant(P<0.05).The scores of dry eye,red eye,burning sensation,foreign body sensation and blurred vision in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).The incidence of clinical adverse reactions in the observation group was 8.82%,which was lower than 11.76%in the control group,but the difference was not statistically significant(P>0.05).Conclusion Eyelid hot compress,meibomian gland massage combined with tobradex ointment is effective in the treatment of dry eye caused by meibomian gland dysfunction,which can improve the total effective rate of treatment,relieve clinical symptoms in a short time,increase tear secretion,delay tear film rupture time,and do not increase clinical adverse reactions.

关 键 词：眼睑热敷 典必殊眼膏 睑板腺功能障碍性干眼症 睑板腺 

分 类 号：R77[医药卫生—眼科]