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作 者:李世军[1,2] 王双珍[2] 杜娟[1] 王晨[1] 张建中 金江[1] LI Shijun;WANG Shuangzhen;DU Juan;WANG Chen;ZHANG Jianzhong;JIN Jiang(Department of Dermatology,Peking University People’s Hospital,Beijing 100044,China;Department of Dermatology,Lyuliang Peoplefs Hospital,Lyuliang 033000,China)
机构地区:[1]北京大学人民医院皮肤科,北京100044 [2]吕梁市人民医院皮肤科,山西吕梁033000
出 处:《中国皮肤性病学杂志》2022年第3期341-342,共2页The Chinese Journal of Dermatovenereology
摘 要:患者男,65岁,鼻部皮疹2年,加重6个月,破溃1个月,外院曾诊断为玫瑰痤疮并行激光治疗。皮肤科情况:鼻部大片暗红斑,其上毛细血管明显扩张,呈线状近平行排列;鼻尖背部增生明显,欠对称,触之坚实;左侧鼻孔明显受压,表面可见破溃结痂。皮损组织病理示:真皮内可见巢片状生长的鳞状上皮细胞团块,细胞异型及核异型明显,核分裂易见,可见角珠,局灶可见浸润性生长。诊断:鳞状细胞癌。A 65-year-old male presented with nasal rash for 2 years,which was aggravated for 6 months and ruptured for 1 month.He was previously diagnosed with rosacea in other hospitals and received laser treatment.Dermatological examination showed large area of dark erythema on the nose,with linear dilation of capillaries,solid asymmetric hyperplasia of nasal tip and back,and obvious compression of left nostril,with rupture and scab on the surface.Histopathological examination showed nests of squamous epithelial cells in the dermis,with marked cell and nuclear atypia,mitosis,keratinization and focal infiltrative growth.The patient was diagnosed with squamous-cell carcinoma.
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