急下存阴法治疗脓毒症急性胃肠损伤的研究进展  

Research progress on sepsis-related acute gastrointestinal injury treated by timely purgation to preserve yin method

作　　者：吴歆頔 钱风华[2] 李璟[3] 赵雷[2] 严理[2] 沈梦雯[2] 钱义明[2] 王珂 周嘉 WU Xindi;QIAN Fenghua;LI Jing;ZHAO Lei;YAN Li;SHEN Mengwen;QIAN Yiming;WANG Ke;ZHOU Jia(Yueyang Clinical Medical College of Shanghai University of Traditional Chinese Medicine,Shanghai,201203;Department of Emergency Medicine,Yueyang Integrated Traditional Chinese and Western Medicine Hospital of Shanghai University of Traditional Chinese Medicine,Shanghai,200437;Department of Acupuncture,Yueyang Integrated Traditional Chinese and Western Medicine Hospital of Shanghai University of Traditional Chinese Medicine,Shanghai,200437;Clinical Research Office of Acupuncture and Anesthesia,Yueyang Integrated Traditional Chinese and Western Medicine Hospital of Shanghai University of Traditional Chinese Medicine,Shanghai,200437;Department of Cardiothoracic Surgery,Yueyang Integrated Traditional Chinese and Western Medicine Hospital of Shanghai University of Traditional Chinese Medicine,Shanghai,200437)

机构地区：[1]上海中医药大学岳阳临床医学院,上海201203 [2]上海中医药大学附属岳阳中西医结合医院急诊医学科,上海200437 [3]上海中医药大学附属岳阳中西医结合医院针灸科,上海200437 [4]上海中医药大学附属岳阳中西医结合医院针麻临床研究办公室,上海200437 [5]上海中医药大学附属岳阳中西医结合医院心胸外科,上海200437

出　　处：《实用临床医药杂志》2022年第6期134-138,144,共6页Journal of Clinical Medicine in Practice

基　　金：上海市进一步加快中医药事业发展三年行动计划中医药传承创新平台建设项目[ZY(2018-2020)-FWTX-6012]。

摘　　要：脓毒症是重症医学的常见病,其病因复杂,病势凶险,并与脏器损伤密切关联,尤其以胃肠功能障碍为多见。急性胃肠损伤(AGI)新定义是以危重症为前提。中医学认为脓毒症属于急性热病,其主要病机是热、毒、瘀、虚,极度伤津耗气,以虚证为甚;AGI则表现为腹胀、便秘、口燥咽干,为实热证。因此,脓毒症AGI病机复杂,阴阳互损、寒热夹杂、本虚标实,根据六经辨证,此病属于少阴三急下证,治以急下存阴法。本文就急下存阴法在脓毒症AGI临床诊治中的运用及研究进展进行综述。Sepsis is a common disease in critical medicine,its etiology is complex,disease situation is dangerous,and it is closely associated with organ injury,especially gastrointestinal dysfunction.The new definition of acute gastrointestinal injury(AGI)is based on critically ill.In traditional Chinese medicine,sepsis is considered as acute fever,and its main pathogenesis is heat,poison,blood stasis and deficiency,especially deficiency syndrome.AGI shows abdominal distension,constipation,dry mouth and pharynx,which is the syndrome of excess heat.Therefore,pathogenesis of AGI of sepsis is complex,with the mutual loss of yin and yang,the mixture of cold and heat,and deficiency of origin and excess of reality.According to syndrome differentiation of six channels,this syndrome belongs to three emergent purging of Shaoyin syndrome,which is treated by timely purgation to preserve yin method.This article reviewed the application and research progress of timely purgation to preserve yin method in clinical diagnosis and treatment of AGI in sepsis.

关 键 词：脓毒症 急性胃肠损伤 急下存阴 少阴三急下证 

分 类 号：R573[医药卫生—消化系统] R285.6[医药卫生—内科学]