神经Sweet病的诊治研究进展  

Recent advance in diagnosis and treatment of neuro-Sweet disease

作　　者：金小琳 田力[2] 滕伟禹[1] Jin Xiaolin;Tian Li;Teng Weiyu(Department of Neurology,First Affiliated Hospital of China Medical University,Shenyang 110001,China)

机构地区：[1]中国医科大学附属第一医院神经内科,沈阳110001 [2]中国医科大学附属盛京医院老年病科,沈阳110004

出　　处：《中华神经医学杂志》2022年第3期312-315,共4页Chinese Journal of Neuromedicine

基　　金：辽宁省科技计划项目(2020JH1/10300002)。

摘　　要：Sweet综合征是一种以发热、嗜中性粒细胞计数升高、皮肤红斑为主要特征的罕见疾病,当中枢神经系统受累时又被称为神经Sweet病(NSD)。该病的临床表现具有高度异质性,脑炎或脑膜炎是最常见的神经系统症状;颅脑MRI检查可无特异性改变,或病灶处有异常信号改变,增强扫描可见病灶环形强化;对激素治疗敏感,但易在激素减量过程中复发。笔者现围绕NSD的临床特点、诊断、治疗及预后等方面的研究进展进行综述,以期提高临床医生对该罕见疾病的认识。Sweet's syndrome(SS)is a rare disease characterized by fever,elevated neutrophil count and skin erythema.When the central nervous system is involved,it is called neuro-Sweet disease(NSD).The clinical manifestations of NSD are highly heterogeneous.Encephalitis or meningitis are the most common neurological manifestations.There can be no specific changes or abnormal signal changes in the focus in brain magnetic resonance imaging(MRI).Circular enhancement of the focus can be seen on enhanced scanning.The disease is sensitive to hormone therapy,but it is easy to relapse in the process of hormone reduction.In order to improve clinicians'understanding of this rare disease,our study systematically reviews the clinical manifestations,diagnosis,treatments and prognoses of NSD.

关 键 词：神经Sweet病 SWEET综合征 脑炎 脑膜炎 

分 类 号：R741[医药卫生—神经病学与精神病学]