松果体实质细胞肿瘤的影像特征及鉴别诊断  

Imaging features and differential diagnosis of pineal parenchymal cell tumors

作　　者：陈楚瑶 许乙凯[1] 林炳权[1] CHEN Chuyao;XU Yikai;LIN Bingquan(Imaging Center,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China)

机构地区：[1]南方医科大学南方医院影像中心,广东广州510515

出　　处：《分子影像学杂志》2022年第2期229-234,共6页Journal of Molecular Imaging

基　　金：广东省基础与应用基础研究基金(2022A1515010373)。

摘　　要：目的 探讨松果体实质细胞肿瘤的CT及MRI影像特征。方法 收集本院34例松果体实质细胞肿瘤的CT、MRI及临床资料,根据病理结果将病例分为3组:松果体细胞瘤(PC组,n=9)、中间分化型松果体实质细胞肿瘤(PPTID组,n=14)和松果体母细胞瘤(PB组,n=11);使用单因素方差分析及卡方检验对3组病例的影像观察指标进行统计学分析。结果 松果体实质细胞肿瘤以边界清楚、形态规则的T1WI低信号、T2WI高信号、明显强化为主要表现,扩散加权成像呈高信号,磁共振波谱成像示Cho/NAA比值升高。3组肿瘤患者的年龄(P=0.009)及囊变(P=0.047)情况差异有统计学意义。将年龄及囊变情况进一步行两两比较,结果显示PB组患者年龄较PPTID(P=0.007)及PC组(P=0.007)小,而PC组发生囊变较PB组(P=0.019)低。结论 松果体实质细胞瘤具有一定的临床特征,3种病理类型具有一定影像差异,通过影像学方法有助于鉴别其病理类型。Objective To investigate the CT and MRI features of pineal parenchymal cell tumors. Methods CT, MRI and clinical data of 34 cases of pineal parenchymal cell tumor in our hospital were collected. The patients were divided into three groups according to the pathological results: pineocytoma(PC group), moderately differentiated pineal parenchymal cell tumor(PPTID group) and pineoblastoma(PB group). Results Pineal parenchymal tumors were mainly characterized by well-defined,regular shape of low signal intensity on T1WI, high signal intensity on T2WI, and significant enhancement, high signal intensity on diffusion-weighted imaging, and elevated Cho/NAA ratio on magnetic resonance spectroscopy. Among the three groups cases, there were significant differences in age(P=0.009) and cystic degeneration(P=0.047). We found that the age of patients with PB were younger than that in both PPTID group(P=0.007) and PC group(P=0.007), while cystic changes occurred less frequently in the PC group than in the PB group(P=0.019). Conclusion With certain clinical and imaging features,pathological types of pineal parenchymal tumors can be identify with the help of CT and MRI technology.

关 键 词：脑肿瘤 松果体 松果体实质细胞肿瘤 计算机断层扫描 磁共振成像 

分 类 号：R739.4[医药卫生—肿瘤]