双膦酸盐对正畸牙根吸收和修复相关细胞作用的研究进展  

The research progress of bisphosphonates on cells related to orthodontic root resorption and repair

作　　者：肖逸雯 申秦颢 尹康[3] Xiao Yiwen;Shen Qinhao;Yin Kang(Department of Stomatology,Hubei Third People's Hospital of Jianghan University 430030,China;Department of Periodontology,Affiliated Stomatology Hospital of Kunming Medical University 650106,China;Department of Orthodontics,Affiliated Stomatology Hospital of Kunming Medical University 650106,China)

机构地区：[1]江汉大学附属湖北省第三人民医院口腔科,武汉430030 [2]昆明医科大学附属口腔医院牙周科,昆明650106 [3]昆明医科大学附属口腔医院正畸科,昆明650106

出　　处：《中华口腔正畸学杂志》2022年第1期33-36,共4页Chinese Journal of Orthodontics

基　　金：云南省科技厅基础研究计划(2019FE001(-250))。

摘　　要：牙根吸收是正畸治疗中常见并发症之一,其高发性已引起正畸医师的关注。双膦酸盐一类骨吸收抑制剂,能调节体内钙代谢。近年来,有研究证实双膦酸盐能有效缓解正畸导致的牙根吸收。本文就双膦酸盐的生物学性状和应用,以及对牙根吸收和修复相关细胞的影响进行综述。Root resorption is a common complication in orthodontic treatment,and its high incidence has attracted the attention of orthodontists.Bisphosphonates which is a bone resorption inhibitor,can regulate calcium metabolism in vivo.In recent years,studies have confirmed that bisphosphonates can effectively alleviate the root resorption caused by orthodontics.This article reviews the biological characteristics and application of bisphosphonates,as well as their effects on cells related to root resorption and repair.

关 键 词：双膦酸盐 牙根吸收 牙根修复 口腔正畸 

分 类 号：R783.5[医药卫生—口腔医学]