^(125)I粒子支架治疗恶性梗阻性黄疸支架通畅时间的影响因素分析  

Analysis of factors affecting the patency time of the^(125)I seeds stent in malignant obstructive jaundice

作　　者：彭赵宏 张德志[1] 施万印[1] 赵本胜[1] 熊壮[1] 汪名权[1] 宋文[1] 陶龙香 刘斌[1] 张帅[1] 程翔[1] Peng Zhaohong;Zhang Dezhi;Shi Wanyin;Zhao Bensheng;Xiong Zhuang;Wang Mingquan;Song Wen;Tao Longxiang;Liu Bin;Zhang Shuai;Cheng Xiang(Dept of Radiology,The First Affiliated Hospital of Anhui Medical University,Hefei 230022)

机构地区：[1]安徽医科大学第一附属医院放射科,合肥230022

出　　处：《安徽医科大学学报》2022年第4期645-649,共5页Acta Universitatis Medicinalis Anhui

基　　金：国家自然科学基金(编号:81873916)。

摘　　要：目的探讨影响恶性梗阻性黄疸^(125)I粒子支架植入术后支架通畅时间的相关的危险因素。方法回顾性分析行胆道^(125)I粒子支架植入的113例恶性梗阻性黄疸患者资料,选择性别、年龄、梗阻部位、^(125)I粒子支架类型、原发肿瘤类型以及术后是否对原发肿瘤进一步治疗作为研究参数,评估影响该类患者^(125)I粒子支架通畅时间的相关危险因素。结果单因素分析显示胆道梗阻部位、^(125)I粒子支架类型、原发肿瘤类型以及术后是否对原发肿瘤进一步治疗是影响支架通畅时间的主要因素(P<0.001);Cox多因素回归分析显示胆道梗阻部位、^(125)I粒子支架类型、是否针对原发肿瘤进一步治疗是影响支架通畅时间的独立因素(P<0.001)。结论多因素分析显示,胆道梗阻部位、^(125)I粒子支架类型、是否针对原发肿瘤进一步治疗是影响恶性梗阻性黄疸支架通畅时间的独立危险因素,对评估该方法治疗的患者预后有重要的参考意义。Objective To investigate the risk factors affecting the patency time of the^(125)I seeds stent in malignant obstructive jaundice.Methods A retrospective analysis of 113 patients with malignant obstructive jaundice underwent biliary tract^(125)I seeds stent implantation.The gender,age,obstruction site,type of^(125)I seeds stent,primary tumor type,and postoperative response to treatment of tumor were enrolled for analysis to evaluate the related risk factors affecting the patency time of the stent.Results Univariate analysis showed that the location of biliary obstruction,the type of^(125)I seeds stent,the type of primary tumor,and the type of primary tumor were the main factors affecting the patency time of the stent(P<0.001);Cox multivariate regression analysis showed biliary obstruction location,the type of^(125)I seeds stent,and whether the primary tumor treated were independent factors that affected the patency time of the stent(P<0.001).Conclusion Multi-factor analysis shows that the location of biliary obstruction,the type of^(125)I seeds stent,and the primary tumor are independent risk factors that affect the patency of the stent for malignant obstructive jaundice,which shows important markers for evaluating the prognosis of patients treated with this method.

关 键 词：恶性梗阻性黄疸 胆道^(125)I粒子支架 支架通畅时间 危险因素 

分 类 号：R735.8[医药卫生—肿瘤]