3987例新生儿眼底筛查结果分析  

Analysis of RetcamⅢFundus Screening Results of 3987 Neonates

作　　者：胡婕[1] 成洋阳[1] 曾亚薇[1] 石晶[1] HU Jie;CHENG Yang-yang;ZENG Ya-wei(Department of Pediatric Ophthalmology and Otorhinolaryngology,Hunan Provincial Maternal and Child Health Care Hospital,Changsha,Hunan 410008,China)

机构地区：[1]湖南省妇幼保健院儿童五官科,湖南长沙410008

出　　处：《医学临床研究》2022年第3期422-424,428,共4页Journal of Clinical Research

摘　　要：【目的】分析3987例新生儿眼底筛查结果。【方法】回顾性分析2017年1月至2019年12月在本院行广域数字化眼底成像系统(RetcamⅢ)眼底筛查的3987例足月新生儿的临床资料,收集眼底检查结果、分娩分式以及出生体重等资料。【结果】3987例足月新生儿筛查结果显示:1020例存在眼底病变,异常率达25.58%,其中视网膜出血占18.46%(736/3987),周边视网膜白色渗出占5.84%(233/3987),可疑家族性渗出性玻璃体视网膜病变占0.48%(19/3987),视网膜色素痣占0.33%(13/3987),白化病眼底改变占0.20%(8/3987),视网膜色素脱失占0.15%(6/3987),永存胚胎血管占0.15%(6/3987),脉络膜缺损占0.08%(3/3987),视网膜劈裂占0.05%(2/3987),视网膜母细胞瘤占0.03%(1/3987)。新生儿视网膜出血与分娩方式、出生体重相关(P<0.05)。致盲性眼病发病率占0.78%(31/3987),包括家族性渗出性玻璃体视网膜病变19例、永存胚胎血管6例、脉络膜缺损3例、视网膜劈裂2例和视网膜母细胞瘤1例。【结论】多种类型的眼底病变可出现在足月新生儿中,且发病率较高,采用RetcamⅢ进行新生儿眼底筛查,有助于早期发现、早期干预眼底病变,降低儿童眼盲与低视力的发生率。【Objective】Based on data from the utilization of wide-area digital fundus imaging system(RetcamⅢ)for full-term neonates fundus screening,this thesis aims to explore its application value by systematic analyzing clinical data arrays.【Methods】Clinical data of 3987 full-term newborns in Hunan Provincial Maternal and Child Health Care Hospital from January 2017 to December 2019 were retrospectivelyanalyzed to link RetcamⅢfundus screening results with birth weight and delivery methods.【Results】Among the 3987 full-term newborns who completed the RetcamⅢexamination,a total of 1020 of them had fundus lesions,therefore the abnormality rate was 25.58%.Among those fundus neonates,there were 736 cases of retinal hemorrhage(18.46%),233 cases of retinal exudative changes(5.84%),19 cases of suspected familial exudative vitreoretinopathy(0.48%),13 cases of retinal pigmented nevus(0.33%),8 cases of albinism with fundus change(0.20%),6 cases of loss of retinal pigment(0.15%),6 cases of persistent fetal vasculature(0.15%),3 cases of choroidal coloboma(0.08%),2 cases of retinoschisis(0.05%)and 1 case of retinoblastoma(0.03%).Neonatal retinal hemorrhage was associated with mode of delivery and birth weight(P<0.05).The incidence of blinding eye diseases accounted for 0.78%(31/39870),including 19 cases of familial exudative vitreoretinopathy,6 cases of persistent fetal vasculature,3 cases of choroidal coloboma,2 cases of retinoschisis and 1 case of retinoblastoma.【Conclusion】Various types of fundus lesions can appear in full-term neonates with a rather high rate of abnormal screening incidence.The utilization of RetcamⅢis a very efficient method for fundus defects early detection and diagnosis to give patients a better chance to avoid blindness and low vision.

关 键 词：眼底 眼疾病/诊断 婴儿 新生 回顾性研究 

分 类 号：R771[医药卫生—眼科]