强迫症患者的病情程度与源检测能力、认知融合、正念的关系  

Relation of obsessive-compulsive severity to ability of source monitoring,cognitive fusion,and mindfulness in patients with obsessive-compulsive disorder

作　　者：孙立阳 刘健 唐文新[3] 朱丞[3] 徐莲莲[3] 赵侠[4] SUN Liyang;LIU Jian;TANG Wenxin;ZHU Cheng;XU Lianlian;ZHAO Xia(School of Mental Health and Psychological Sciences,Anhui Medical University,Hefei 230032,China;Department of Science and Education,Hangzhou Seventh People's Hospital,Hangzhou 310013,China;Psychiatry Department IV,Hangzhou Seventh People's Hospital,Hangzhou 310013,China;Hangzhou Fuyang District Third People's Hospital,Hang zhou 311400,China)

机构地区：[1]安徽医科大学精神卫生与心理科学学院,合肥230032 [2]杭州市第七人民医院科教部,杭州310013 [3]杭州市第七人民医院精神四科,杭州310013 [4]杭州市富阳区第三人民医院,杭州311400

出　　处：《中国心理卫生杂志》2022年第5期397-403,共7页Chinese Mental Health Journal

基　　金：浙江省自然科学基金(LGF19H090015);杭州市科技型中小企业技术创新基金(20180533B83)。

摘　　要：目的:探索强迫症患者病情严重程度与源检测能力、认知融合、正念之间的关系。方法:选取符合精神障碍诊断与统计手册第5版(DSM-5)强迫症诊断标准的患者(最近8周未接受药物治疗)35例,同时招募正常对照35例。使用源检测三键任务范式、耶鲁-布朗强迫症状维度量表(Y-BOCS)、认知融合问卷(中文版)(CFQ)及正念注意觉知量表(MAAS)进行测评。源检测能力指标用平均条件化源辨别测量(ACSIM)。结果:强迫症患者ACSIM、MAAS得分均低于正常对照组,CFQ得分高于正常对照组,(均P<0.001)。逐步回归分析显示,所有被试的ACSIM得分与Y-BOCS得分负向关联(β=-30.67,P<0.01),CFQ得分与Y-BOCS得分正向关联(β=0.54,P<0.01)。结论:强迫症患者的病情严重程度与源检测能力、认知融合关系紧密。Objective:To explore the relation of obsessive-compulsive severity to the ability of source monitoring,cognitive fusion and mindfulness in patients with obsessive-compulsive disorder.Methods:Thirty-five patients with obsessive-compulsive disorder meeting the Diagnostic and Statistical Manual of Mental Disorders,5 th Edition(DSM-5)criteria(had not taken OCD medication in the last 8 weeks)and 35 normal controls were recruited.They were assessed with the three-button task paradigm of source monitoring,Yale-Brown scale for Obsessive-Compulsive Symptoms(Y-BOCS),Cognitive Fusion Questionnaire(CFQ)and Mindful Attention Awareness Scale(MAAS).The discriminating ability index of source monitoring was measured by means of Average Conditional Source Identification Measure(ACSIM).Results:The ACSIM and MAAS scores were lower,and the CFQ scores were higher in patients with OCD than in normal controls(P<0.001).Stepwise regression showed that in all participants the ACSIM scores were negatively correlated with the Y-BOCS scores(β=-30.67,P<0.01),and the CFQ scores were positively correlated with the Y-BOCS scores(β=0.54,P<0.01).Conclusion:It suggests that the severity of obsessive-compulsive is closely related to the ability of source monitoring and cognitive fusion in patients with OCD.

关 键 词：强迫症 源检测 认知融合 正念 

分 类 号：R749.72[医药卫生—神经病学与精神病学]