Hoesch反应合成2,3,4-三羟基二苯甲酮和2,4,6-三羟基二苯甲酮  

Synthesis of 2,3,4-trihydroxy Benzophenone and 2,4,6-trihydroxy Benzophenone by Hoesch Reaction

作　　者：雷响 郑德勇[1] LEI Xiang;ZHENG De-yong(College of Material Engineering,Fujian Agriculture and Forestry University,National Forestry and Grassland Administration Key Laboratory of Plant Fiber Functional Materials,Fujian Fuzhou 350002,China)

机构地区：[1]福建农林大学材料工程学院,植物纤维功能材料国家林业和草原局重点实验室,福建福州350002

出　　处：《广州化工》2022年第7期58-61,共4页GuangZhou Chemical Industry

基　　金：福建农林大学科技创新专项基金项目(No:CXZX2017036);中央财政林业科技推广示范项目(No:闽[2019]TG17号)。

摘　　要：分别以焦性没食子酸和间苯三酚为原料,乙酸乙酯为溶剂,在氯化氢和ZnCl_(2)催化下与苯甲腈发生Hoesch反应,合成2,3,4-三羟基二苯甲酮和2,4,6-三羟基二苯甲酮,其紫外光谱的最大吸收峰分别在308和311 nm,摩尔吸光系数分别为1.535×10^(4)和1.297×10^(4)L/cm·mol,均是良好的UVB段紫外线吸收剂。考察了原料配比、ZnCl_(2)用量、反应时间和反应温度对Hoesch反应的影响,得到较佳的反应条件为原料配比n(酚):n(腈)为1:1.05、ZnCl_(2)用量为0.0175 mol、反应时间为28 h、反应温度为10℃。The ultraviolet absorbers 2,3,4-trihydroxydiphenenone and 2,4,6-hydroxydiphenenone were synthesized by Hoesch reaction of pyrogallic acid and phloroglucinol with benzonitrile catalyzed by hydrogen chloride and ZnCl_(2),respectively.UV spectra showed that the maximum absorption peaks at 308 and 311 nm,moore absorption coefficients were 1.535×10^(4) and 1.297×10^(4) L/cm·mol,respectively.The effects of the ratio of raw materials,the amount of ZnCl_(2),reaction time and reaction temperature on Hoesch reaction were investigated.

关 键 词：Hoesch反应 焦性没食子酸 三羟基二苯甲酮 紫外线吸收剂 摩尔吸收系数 

分 类 号：TQ244.5[化学工程—有机化工]