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作 者:吴会晓 蔡毅东[1] WU Huixiao;CAI Yidong(Department of Spleen and Stomach Diseases,Xiyuan Hospital of China Academy of Chinese Medical Sciences,Beijing 100091,China)
机构地区:[1]中国中医科学院西苑医院脾胃病科,北京100091
出 处:《中国医药导报》2022年第11期16-20,共5页China Medical Herald
基 金:国家重点研发计划(2016YFC1302203);北京市科技计划重点项目(D161100005116004)。
摘 要:目的采用可视化软件CiteSpace分析中医药治疗溃疡性结肠炎(UC)的研究现状和发展趋势。方法检索中国知网、万方和维普数据库2000年1月至2021年10月的相关文献,通过CiteSpace 5.8.R1对文献的时间、作者、研究机构、关键词进行可视化分析。结果共纳入文献3135篇,整体发文量呈现上升趋势;核心作者以沈洪、王新月、唐志鹏为代表;主要研究机构有南京中医药大学、北京中医药大学、上海中医药大学附属龙华医院等;频次排名前3位的关键词为UC、保留灌肠和中医药疗法;研究热点集中于UC的中医辨证用药、中医药治疗UC的临床效果研究及机制探索。结论知识图谱直观地展现了中医药治疗UC近21年来的研究现状,分析得出未来研究会在作用机制方面深入,且信号通路、肠道菌群、炎症因子是未来的研究热点和趋势。Objective To analyze the research status and development trend of traditional Chinese medicine in the treatment of ulcerative colitis through the visualization software CiteSpace.Methods Related articles were retrieved from China National Knowledge Infrastructure,Wanfang,and VIP databases from January 2000 to October 2021,visualized analysis was conducted with authors,research institutions,and keywords of the articles through CiteSpace 5.8.R1.Results A total of 3135 articles were included,and the overall number of articles presented an upward trend;the core authors were Shen Hong,Wang Xinyue,and Tang Zhipeng;the main research institutions included Nanjing University of Chinese Medicine,Beijing University of Chinese Medicine,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine;the top three keywords were UC,retention enema,and traditional Chinese medicine therapy;the focus of domestic research was the use of UC in traditional Chinese medicine syndrome differentiation,the study of the clinical efficacy and mechanism exploration of traditional Chinese medicine in the treatment of UC.Conclusion The knowledge map directly shows the research status of traditional Chinese medicine treatment of UC in the past 21 years,the analysis shows that research will go further on the mechanism of action,and the signaling pathway,intestinal flora,and inflammatory factors are the research hot spots and trends in the future.
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