成功老龄、正常老龄及轻度认知障碍老龄人群认知功能的比较  

Comparison of cognitive function among successful aging population,normal aging population and old population with mild cognitive impairment

作　　者：吴雪桉 赵幸福[2] 韩胜楠 汪腾龙 WU Xue-an;ZHAO Xing-fu;HAN Sheng-nan;WANG Teng-long(School of Humanities and Management,Wannan Medical College,Wuhu 241002,China;Wuxi Mental Health Center,Wuxi 214151,China)

机构地区：[1]皖南医学院人文与管理学院,安徽省芜湖市241002 [2]江苏省无锡市精神卫生中心,无锡市214151

出　　处：《广西医学》2022年第3期249-252,共4页Guangxi Medical Journal

基　　金：江苏省重点研发专项课题(BE2017624)。

摘　　要：目的比较成功老龄人群、正常老龄人群与轻度认知障碍(MCI)老龄人群的认知功能。方法将60岁及以上的102例老年人根据简易精神状态检查(MMSE)量表及日常生活能力量表(ADL)评分分为成功老龄组35例、正常老龄组35例以及MCI组32例。比较3组研究对象的人口学资料及核心神经心理测验(CNT)量表评分。结果3组老年人的文化程度差异有统计学意义(P<0.05),而3组的年龄、性别、婚姻状况、居住方式差异均无统计学意义(均P>0.05)。CNT量表中数字广度、图符配对、言语类推、数理运算、快速组词因子的评分由高到低均为成功老龄组>正常老龄组>MCI组,且成功老龄组快速编码、图画回忆、连线测验因子的评分均高于正常老龄组与MCI组(均P<0.05)。结论相比于正常老龄及MCI老龄人群,成功老龄人群的文化程度水平与认知功能均相对较高,提示丰富的知识储备对认知功能的保持可能存在积极的影响。Objective To compare the cognitive function among successful aging population,normal aging population and population with mild cognitive impairment(MCI).Methods A total of 102 elderly people aged 60 and over were divided into successful aging group(35 cases),normal aging group(35 cases)and MCI group(32 cases)according to the scores of the Mini-Mental State Examination(MMSE)scale and the Activities of Daily Living Scale(ADL).The demographic data and the core neuropsychological test(CNT)scale scores of research subjects were compared among the three groups.Results There was a statistically significant difference in the elderly people′s educational level among the three groups(P<0.05),whereas there was no statistically significant difference in age,gender,marital status,or living style among the three groups(all P>0.05).The scores for the factors in the CNT scale such as digit span,picture-word matching,linguistic analogy,mathematical calculation,and fast wording decreased in the order of the successful aging group,the normal aging group and the MCI group,and the successful aging group yielded higher scores for the factors,such as fast coding,picture recall,and trail-making test,as compared with the normal aging and MCI groups(all P<0.05).Conclusion Compared with normal aging population and old MCI population,successful aging population possess relatively higher educational level and cognitive function,indicating that a rich knowledge reserve may have a positive impact on the maintenance of the cognitive function.

关 键 词：成功老龄 认知障碍 核心神经测验 认知功能 

分 类 号：R741[医药卫生—神经病学与精神病学]