One-year outcomes and predictable factors for microhook ab interno trabeculotomy  

作　　者：Daiki Sakai Masashi Fujihara Satoshi Yokota Makoto Nakamura Yasuo Kurimoto 

机构地区：[1]Department of Ophthalmology,Kobe City Eye Hospital,Kobe 650-0047,Japan [2]Department of Ophthalmology,Kobe City Medical Center General Hospital,Kobe 650-0047,Japan [3]Department of Surgery,Division of Ophthalmology,Kobe University Graduate School of Medicine,Kobe 650-0017,Japan

出　　处：《International Journal of Ophthalmology(English edition)》2022年第4期598-603,共6页国际眼科杂志（英文版）

摘　　要：AIM: To investigate the one-year outcomes and factors that influence the results of microhook ab interno trabeculotomy(μLOT). METHODS: The medical records of consecutive patients with open angle glaucoma who underwent μLOT(including combination of μLOT and cataract surgery) between Februar y 2018 and July 2019 were retrospectively reviewed. Surgical success was defined as the following: an intraocular pressure(IOP)≤21 mm Hg or IOP≤preoperative IOP with a reduced number of glaucoma eye drops, without additional glaucoma surgery, and assessed using KaplanMeier survival analysis. A multivariate Cox proportionalhazards regression model was used to investigate the factors associated with surgical failure.RESULTS: The 59 eyes of 59 patients comprising 28 eyes with primary open angle glaucoma(POAG) and 31 with secondary open angle glaucoma(SOAG) were included. The mean IOP and number of glaucoma eye drops significantly decreased from 25.3±7.2 mm Hg and 3.9±1.1, preoperatively to 16.1±4.4 mm Hg(P<0.01) and 2.1±1.8(P<0.01),respectively, 12 mo postoperatively, with a cumulative success rate of 63.1%. The one-year success rate was significantly higher in POAG eyes than in SOAG eyes(80.0% vs 48.0%;P=0.011, log-rank test). Multivariate analyses revealed SOAG [P=0.017, adjusted hazard ratio(a HR): 3.468, 95%CI: 1.246-9.654] and the postoperative IOP spike(IOP>25 mm Hg within 2 wk post-surgery;P<0.001, a HR: 5.382, 95%CI:2.113-13.707) as independent factors associated with surgical failure.CONCLUSION: The μLOT is a good treatment option for POAG eyes. However, the postoperative course should be carefully followed in cases with postoperative IOP spike.

关 键 词：microhook ab interno trabeculotomy TRABECULOTOMY ab interno minimally invasive glaucoma surgery survival analysis 

分 类 号：R779.6[医药卫生—眼科]