烟草及其制品中游离烟碱的测定方法研究进展  

Research progress on the determination of free-base nicotine in tobacco and tobacco products

作　　者：张浩 韩书磊[1] 陈欢[1] 侯宏卫[1] 胡清源[1] ZHANG Hao;HAN Shu-lei;CHEN Huan;HOU Hong-wei;HU Qing-yuan(China National Tobacco Quality Supervision and Test Centre,Key Laboratory of Tobacco Biological Effects,Zhengzhou,Henan 450001,China)

机构地区：[1]国家烟草质量监督检验中心烟草生物学效应重点实验室,河南郑州450001

出　　处：《食品与机械》2022年第4期234-240,252,共8页Food and Machinery

基　　金：中国烟草总公司重大专项项目(编号:110202101018〔XX-04〕,110202001007〔XX-03〕);国家烟草质量监督检验中心烟草控制框架公约科技项目(编号:552018AQ0090)。

摘　　要：综述了近30年烟草及其制品中游离烟碱含量测定方法的研究进展,包括溶剂萃取法、顶空固相微萃取法、核磁共振法、Henderson-Hasselbalch法和光谱法等,总结了各个方法的优缺点,并展望了烟草及其制品中游离烟碱含量检测方法未来的研究方向。The research progress on determination of free-base nicotine in tobacco and tobacco products in the past 30 years was reviewed and discussed,including solvent extraction method,headspace solid-phase microextraction method,^(1)H NMR,Henderson-Hasselbalch method and spectroscopy method,etc.Advantages and limitations of each method were summarized and discussed and the development in this field was prospected.

关 键 词：游离烟碱 溶剂萃取法 顶空固相微萃取法 核磁共振法 Henderson-Hasselbalch法 光谱法 

分 类 号：TS411[农业科学—烟草工业] O652[理学—分析化学]