肾癌增强CT肾脏皮质厚度与肾功能的相关性  

Correlation Between Renal Cortical Thickness and Renal Function in Patients with Renal Cell Carcinoma by Enhanced CT

作　　者：唐姗姗[1] 潘爱珍[1] 李勤祥[1] 余田[1] 陈颖瑜[1] 徐志锋[1] 叶亚君[1] 李雪莲[1] Tang Shanshan;Pan Aizhen;Lt Qinxiang;Yu Tian;Chen Yingyu;Xu Zhifeng;Ye Yajun;Li Xuelian(Department of Radiology,The First People's Hospital of Foshan City,Guangdong Province,Foohan,Guangdong 528000)

机构地区：[1]广东省佛山市第一人民医院放射科,广东佛山528000

出　　处：《现代医用影像学》2022年第2期210-214,共5页Modern Medical Imageology

基　　金：广东省佛山市科技创新新项目,编号:1920001001371。

摘　　要：目的:探讨肾癌增强CT肾脏皮质厚度与肾功能的相关性。方法:研究时间为2014年2月到2020年1月,选择在我院进行诊治的肾实质内病变患者78例作为研究对象,其中肾癌28例(肾癌组)与肾良性病变50例(良性组),两组都给予增强CT检查,记录CT成像常规参数、肾脏皮质厚度,同时记录与检测患者的肾功能并进行相关性分析。结果:肾癌组的BF、BV、PS值高于良性组,MTT值低于良性组,肾癌组的GFR值低于良性组,MVD计数与VEGF表达率高于良性组,对比差异都有统计学意义(P<0.05)。肾癌组的肾脏皮质厚度与肾皮质CT增强值都显著少于良性组(P<0.05)。在肾癌组中,Pearson相关分析显示GFR、MVD、VEGF与肾皮质CT增强值、肾脏皮质厚度、PS、MTT都有显著相关性(P<0.05);以皮质厚度≥0.51 cm、0.30-0.50 cm、<0.30cm为判断肾功能正常、轻度减退和重度减退的标准,符合率为67.9%。结论:肾癌的增强CT扫描是一种较为便捷、安全的方法,对肾脏皮质厚度进行测定,有助于对肾功能进行判断,有助于提高临床诊断准确率。Objective:To investigate the correlation between renal cortical thickness and renal function in patients with renal cell carcinoma by enhanced CT.Methods:From February 2014 to January 2020, 78 cases of renal parenchymal lesions were selected in our hospital, of which 28 cases of renal cell carcinoma(renal cell carcinoma group) and 50 cases of benign renal lesions(benign group), two groups were given enhanced CT examination, recorded CT imaging regular parameters, renal cortical thickness. The renal function of the patients were measured and were given the correlation analysis.Results:The value of BF, BV and PS in renal cell carcinoma group were higher than that in benign group, and the value of MTT were lower than that in benign group. The GFR values in the renal cell carcinoma group were lower than that in benign group, and the expression rate of MVD and VEGF were higher than that of the benign group, and compared the difference were statistically significantly(P<0.05). The renal cortical thickness and CT value of renal cortex in the renal cell carcinoma group were significantly less than those in the benign group(P<0.05). In the renal cell carcinoma group, pearson correlation analysis showed that GFR, MVD and VEGF were significant correlation with renal cortical CT enhancement, renal cortical thickness, PS and MTT(P<0.05), and the coincidence rate were 67.9% with the standard of cortical thickness ≥0.51 cm, 0.30-0.50 cm, and <0.30 cm were the criteria for judging normal renal function, mild hypothyroidism and severe hypothyroidism.Conclusion:The enhanced CT of renal cell carcinoma is a convenient and safe method, the measurement of renal cortical thickness can help to judge the renal function and improve the accuracy of clinical diagnosis.

关 键 词：肾癌 增强CT 肾脏皮质厚度 肾功能 相关性 

分 类 号：R737.11[医药卫生—肿瘤] R730.44[医药卫生—临床医学]