疏肝理脾方联合灌肠治疗慢性非特异性溃疡性结肠炎肝郁脾虚证的疗效及对炎症因子、血小板水平的影响  

Curative Effect of Shugan Lipi Decoction Combined with Enema in the Treatment of Chronic Non-Specific Ulcerative Colitis with Liver Depression and Spleen Deficiency Syndrome and its Influence on Inflammatory Factors,Platelets

作　　者：刘晓虹[1] 王永杰 LIU Xiao-hong;WANG Yong-jie(Department of T.C.M,Baoji Maternal and Child health care Hospital,Baoji,721000,China;Department ofInternal medicine,The Traditional Chinese medicine Hospital of Ningqiang County,Ningqiang,724400,China)

机构地区：[1]宝鸡市妇幼保健院中医科,宝鸡721000 [2]宁强县中医医院内科,宁强724400

出　　处：《血栓与止血学》2022年第2期216-218,共3页Chinese Journal of Thrombosis and Hemostasis

摘　　要：目的探讨疏肝理脾方联合灌肠治疗慢性非特异性溃疡性结肠炎(CUC)肝郁脾虚证的疗效及对炎症因子、血小板(BPC)的影响。方法以2018.2-2021.2收治的96例肝郁脾虚证CUC患者为对象,随机分为观察组(疏肝理脾方联合灌肠)与对照组(美沙拉嗪)。对比两组疗效及炎症、BPC水平。结果观察组总有效率为93.75%(45/48),高于对照组70.83%(34/48)(P <0.05)。两组治疗后白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平降低,白介素-10(IL-10)水平升高,观察组IL-6、TNF-α水平低于对照组,IL-10水平高于对照组(P <0.05)。两组治疗后BPC、ESR水平降低,观察组BPC、ESR水平低于对照组(P <0.05)。结论疏肝理脾方结合灌肠治疗肝郁脾虚证CUC患者的效果较好,可抑制机体炎症反应,改善凝血状态。

关 键 词：疏肝理脾方 灌肠 慢性非特异性溃疡性结肠炎 肝郁脾虚证 疗效 

分 类 号：R574.62[医药卫生—消化系统]