Random noise stimulation in the treatment of patients with neurological disorders  

作　　者：Mateo A.Herrera-Murillo Mario Treviño Elias Manjarrez 

机构地区：[1]Facultad de Medicina,Plan de Estudios Combinados en Medicina(PECEM),UNAM,Circuito Interior,Ciudad Universitaria,Av.Universidad,Ciudad de México,México [2]Instituto de Neurociencias,Universidad de Guadalajara,Guadalajara,Jalisco,México [3]Instituto de Fisiología,Benemérita Universidad Autónoma de Puebla,Puebla,México

出　　处：《Neural Regeneration Research》2022年第12期2557-2562,共6页中国神经再生研究（英文版）

基　　金：supported by Cátedra Marcos Moshinsky (to EM);CONACyT Fronteras de la Ciencia#536 (to EM);VIEP-PIFI-FOMES-PROMEP-BUAP-Puebla (to EM);Comitéde Internacionalización de la Investigación (to EM),México

摘　　要：Random noise stimulation technique involves applying any form of energy(for instance,light,mechanical,electrical,sound)with unpredictable intensities through time to the brain or sensory receptors to enhance sensory,motor,or cognitive functions.Random noise stimulation initially employed mechanical noise in auditory and cutaneous stimuli,but electrical energies applied to the brain or the skin are becoming more frequent,with a series of clinical applications.Indeed,recent evidence shows that transcranial random noise stimulation can increase corticospinal excitability,improve cognitive/motor performance,and produce beneficial aftereffects at the behavioral and psychological levels.Here,we present a narrative review about the potential uses of random noise stimulation to treat neurological disorders,including attention deficit hyperactivity disorder,schizophrenia,amblyopia,myopia,tinnitus,multiple sclerosis,post-stroke,vestibular-postural disorders,and sensitivity loss.Many of the reviewed studies reveal that the optimal way to deliver random noise stimulation-based therapies is with the concomitant use of neurological and neuropsychological assessments to validate the beneficial aftereffects.In addition,we highlight the requirement of more randomized controlled trials and more physiological studies of random noise stimulation to discover another optimal way to perform the random noise stimulation interventions.

关 键 词：auditory noise mechanical noise neurological disorders neuronal noise noise galvanic vestibular stimulation non-invasive brain stimulation transcranial electrical stimulation transcranial random noise stimulation 

分 类 号：R741.05[医药卫生—神经病学与精神病学]