上海市精神分裂症住院患者伴代谢异常情况  

Prevalence and clinical characteristics of the metabolic syndrome in of inpatients with schizophrenia in Shanghai

作　　者：甘鸿 彭素芳 陆峥 吴彦 易正辉[1] 杨道良[2] 朱光[3] 屠一敏 张成芳 潘丽红 施冬青 高存友 张展星[8] 吴宇杰[9] 管晓波[10] 江海峰[1] 赵敏[1] GAN Hong;PENG Su-fang;LU Zheng;WU Yan;YI Zheng-hui;YANG Dao-liang;ZHU Guang;TU Yi-min;ZHANG Cheng-fang;PAN Li-hong;SHI Dong-qing;GAO Cun-you;ZHANG Zhan-xing;WU Yu-jie;GUAN Xiao-bo;JIANG Hai-feng;ZHAO Min(Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China)

机构地区：[1]上海交通大学医学院附属精神卫生中心,200030 [2]上海市长宁区精神卫生中心 [3]上海市虹口区精神卫生中心 [4]上海市杨浦区精神卫生中心 [5]上海市浦东新区精神卫生中心 [6]上海市静安区精神卫生中心 [7]上海市嘉定区精神卫生中心 [8]上海市宝山区精神卫生中心 [9]上海市徐汇区精神卫生中心 [10]上海市民政第三精神卫生中心

出　　处：《临床精神医学杂志》2022年第2期126-128,共3页Journal of Clinical Psychiatry

基　　金：上海市精神卫生中心“启航计划”(2018-QH-01);上海市卫生健康委员会卫生行业临床研究专项-青年项目(20194Y0037);上海市科学技术委员会科研计划项目(18411961200)。

摘　　要：目的:探讨上海市精神分裂症住院患者伴代谢异常情况及危险因素分析。方法:收集2020年6月至8月上海市11家精神专科医院精神分裂症住院患者的一般人口学资料(性别、年龄、文化程度、吸烟与饮酒史)及临床资料[首发年龄、病程、服用抗精神病药情况、临床总体印象量表(CGI)评分];采用中华医学会糖尿病学会的代谢综合征(MS)标准对入组者血糖、血压、血脂等指标评估入组者代谢异常状况,并进行比较,分析发生代谢异常的危险因素。结果:共筛查3624例精神分裂症患者,163例患者资料不全不纳入分析。3461例患者中,各项代谢指标正常2357例(代谢正常组);1267例(36.61%)≥1项代谢指标异常(代谢异常组),其中726例(20.98%)符合MS诊断标准,临界状态378例,1项代谢指标异常125例。结论:长期住院的精神分裂症患者发生代谢异常及MS患病风险高。Objective:To investigate the prevalence and clinical characteristics of metabolic syndrome(MS)in schizophrenic inpatients in Shanghai.Method:Patients'data were collected in eleven psychiatric hospitals in Shanghai,including demographic data(gender,age,education level,smoking and drinking history)and clinical data(age of first episode,course of disease,antipsychotic use,Clinical Overall Impression Scale(CGI)score).The blood glucose,blood pressure,plasma lipid were evaluated by MS standard of Chinese Medical Association Diabetes Society,and the metabolic abnormalities of the participants were compared and analyzed.Results:3624 schizophrenic inpatients treated in Shanghai psychiatric hospital were investigated.2357 cases were metabolically healthy;1267 cases(36.61%)suffered from metabolic disorder,among which 726 cases(20.98%)had metabolic syndrome,and 378 cases were in critical state,and 125 cases had one abnormal metabolic index.Conclusion:The MSe is highly prevalent among inpatients with schizophrenia.

关 键 词：精神分裂症 代谢异常 

分 类 号：R749.3[医药卫生—神经病学与精神病学]