腹腔镜直肠全系膜切除术后出现吻合口瘘的相关危险因素分析  

Analysis of Related Risk Factors for Anastomotic Leakage after Laparoscopic Total Mesorectal Excision

作　　者：宋志 熊欢 谈运长 汪峰 孙胜 SONG Zhi;XIONG Huan;TAN Yunchang;WANG Feng;SUN Sheng(The Affiliated Hospital of Jiujiang University,Jiujiang 332000,China;不详)

机构地区：[1]九江学院附属医院,江西九江332000

出　　处：《中国医学创新》2022年第7期151-154,共4页Medical Innovation of China

摘　　要：目的:探讨腹腔镜直肠全系膜切除术(TME)后出现吻合口瘘(AL)的相关危险因素。方法:回顾性分析2018年1月-2021年2月在九江学院附属医院行腹腔镜TME术治疗232例直肠癌患者临床资料。分析腹腔镜TME术后出现AL的相关影响因素。结果:腹腔镜TME术后AL发生率为10.34%(24/232);单因素分析显示,AL组与非AL组在年龄、性别、距肛缘距离、血管浸润、合并肠梗阻与新辅助治疗方面比较,差异均有统计学意义(P<0.05)。多因素分析显示,男性、年龄≥60岁、距肛缘距离<7 cm、血管浸润、合并肠梗阻、新辅助治疗均为腹腔镜TME术后出现AL的高危因素(P<0.05)。结论:腹腔镜TME术后出现AL与年龄、性别、距肛缘距离、血管浸润、合并肠梗阻、新辅助治疗密切相关。Objective: To investigate the risk factors of anastomotic leakage(AL) after laparoscopic total mesorectal excision(TME). Method: The clinical data of 232 patients with rectal cancer who underwent laparoscopic TME in the Affiliated Hospital of Jiujiang University from January 2018 to February 2021were retrospectively analyzed. The related influencing factors of AL after laparoscopic TME were analyzed.Result: The incidence of AL after laparoscopic TME was 10.34%(24/232);univariate analysis showed that there were significant differences in age, gender, distance from anal margin, vascular infiltration, combined intestinal obstruction and neoadjuvant therapy between AL group and non AL group, the differences were statistically significant(P<0.05). Multivariate analysis showed that male, age ≥60 years, distance from anal margin <7 cm,vascular infiltration, combined intestinal obstruction and neoadjuvant therapy were the high risk factors of AL after laparoscopic TME(P<0.05). Conclusion: The appearance of AL after laparoscopic TME is closely related to age, gender, distance from the anal margin, vascular infiltration, combined intestinal obstruction and neoadjuvant therapy.

关 键 词：直肠全系膜切除术 腹腔镜 吻合口瘘 血管浸润 

分 类 号：R735.37[医药卫生—肿瘤]