慢性疾病轨迹干预模式对脑胶质瘤术后患者癌因性疲乏的影响及相关影响因素分析  

Effect of chronic disease trajectory intervention mode on cancer-related fatigue in patients with glioma after surgery and analysis of related influencing factors

作　　者：王永勤[1] 臧珍珍 苏玲[1] WANG Yongqin;ZANG Zhenzhen;SU Ling(Department of Neurosurgery,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,He’nan,China)

机构地区：[1]郑州大学第一附属医院神经外科,郑州4500000

出　　处：《癌症进展》2022年第6期627-630,共4页Oncology Progress

摘　　要：目的探讨慢性疾病轨迹干预模式对脑胶质瘤术后患者癌因性疲乏的影响及相关影响因素分析。方法采用Piper疲乏自评量表评估108例脑胶质瘤患者的癌因性疲乏情况,给予术后发生癌因性疲乏的患者慢性疾病轨迹模式干预,比较干预前后Piper疲乏自评量表评分变化。癌因性疲乏的影响因素采用多因素Logistic回归分析。结果108例脑胶质瘤患者术后发生癌因性疲乏73例,未发生癌因性疲乏35例;慢性疾病轨迹模式干预2周后,73例癌因性疲乏脑胶质瘤患者行为疲乏、情感疲乏、感觉疲乏、认知情绪疲乏评分及总分均明显低于干预前(P﹤0.01)。单因素分析结果显示,发生癌因性疲乏和未发生癌因性疲乏脑胶质瘤患者受教育年限、性格、临床分期、患者是否知晓病情、术后放化疗情况比较,差异均有统计学意义(P﹤0.05)。Logistic回归分析结果显示,受教育年限长、性格内向、临床分期为Ⅲ~Ⅳ期、患者知晓病情、术后放化疗均是脑胶质瘤患者术后发生癌因性疲乏的独立危险因素(P﹤0.05)。结论受教育年限长、性格内向、临床分期为Ⅲ~Ⅳ期、患者知晓病情、术后放化疗均是脑胶质瘤患者术后发生癌因性疲乏的独立危险因素,给予适当的干预措施对及时改善患者的癌因性疲乏程度有一定的临床价值。Objective To explore the effect of chronic disease trajectory intervention mode on cancer-related fatigue in patients with glioma after surgery and analysis of related influencing factors.Method The Piper fatigue self-rating scale was used to evaluate the cancer-related fatigue in 108 patients with glioma.Patients with postoperative cancer-related fatigue were given chronic disease trajectory model intervention,and the scores of Piper fatigue self-rating scale before and after the intervention were compared.The influencing factors of cancer-related fatigue were analyzed by multivariate Logistic regression analysis Result A total of 73 cases of cancer-related fatigue occurred in 108 patients with glioma after operation,and 35 cases of cancer-related fatigue did not occur.After 2 weeks of chronic disease trajectory model intervention,the scores of behavioral fatigue,emotional fatigue,sensory fatigue,cognitive-emotional fatigue and total score of 73 cancer-related fatigue glioma patients were significantly lower than those before intervention(P<0.01).Univariate analysis showed that there were statistically significant differences in years of education,personality,clinical stage,whether the patient was informed,and postoperative radiotherapy and chemotherapy between patients with cancerrelated fatigue and those without fatigue(P<0.05).Logistic regression analysis showed that long years of education,introverted personality,clinical stage III-IV,patient awareness,postoperative radiotherapy and chemotherapy were all independent risk factors for postoperative cancer-related fatigue in patients with glioma(P<0.05).Conclusion High years of education,introverted personality,clinical stage III-IV,patient awareness of the disease,and postoperative radiotherapy and chemotherapy are independent risk factors for cancer-related fatigue in patients undergoing glioma surgery.Appropriate intervention measures can improve the patient’s cancer-related fatigue with a certain clinical value.

关 键 词：脑胶质瘤 癌因性疲乏 影响因素 慢性疾病轨迹干预模式 

分 类 号：R739.47[医药卫生—肿瘤]