新精神活性物质异构体分离分析技术研究进展  

Research progress on separation and analysis technology for isomers of new psychoactive substances

作　　者：胡爽[1,2] 花镇东 程芳彬[4] 刘耀 HU Shuang;HUA Zhendong;CHENG Fangbin;LIU Yao(People’s Public Security University of China,Beijing 100038;Beijing Police College,Beijing 102202;Anti-drug Information Technology Center of the Ministry of Public Security,Beijing 100193;Zhongshan Public Security Bureau,Zhongshan 528403)

机构地区：[1]中国人民公安大学,北京100038 [2]北京警察学院,北京102202 [3]公安部禁毒情报技术中心,北京100193 [4]中山市公安局,中山528403

出　　处：《分析试验室》2022年第4期466-474,共9页Chinese Journal of Analysis Laboratory

基　　金：北京市教育委员会科研计划项目(KM202114019001);北京警察学院科研项目(2021KZD03)资助。

摘　　要：新精神活性物质作为一类新型毒品,其滥用问题对人类健康、公共安全和社会治安造成了巨大危害。新精神活性物质所具备的种类繁多、更新换代迅速、同分异构体庞杂等特点,严重干扰分离分析技术的选择、检测数据的解读。本文首先从基本概况、管控缺失等方面对新精神活性物质滥用现状进行概述;进而着重介绍了其位置异构体和光学异构体常用的分离分析技术,并对各种技术的适用范围、优点和局限性进行了评述。在实际检测过程中,司法鉴定人员应结合检材特性,采用多种独立的检测方法,相互印证,以求得到科学、可靠的鉴定结果。As a new type of drug,new psychoactive substances are harmful to human health,public safety and social order.However,new psychoactive substances have the characteristics of a wide variety,rapid replacement,and a large number of isomers,which seriously interfere with the choice of separation analysis technology and the interpretation of test data.This article firstly provides a brief overview of the current situation of the abuse of new psychoactive substances in terms of lack of control.Furthermore,we emphatically introduced the separation and analysis techniques commonly used in positional isomers and optical isomers,and reviewed their applications,advantages and limitations.In the actual appraisal process,the forensic analysts should master the characteristics of the detection object,and use a variety of independent testing methods to confirm each other in order to obtain scientific and reliable analysis results.

关 键 词：新精神活性物质 同分异构体 分离分析技术 

分 类 号：O656.2[理学—分析化学]