早期宫颈癌患者手术治疗的临床特征与预后分析  

Clinical Characteristics and Prognosis of Eearly Cervical Cancer Patients Undergoing Surgical Treatment

作　　者：林淑玲[1] 李从铸[2] LIN Shu-ling;LI Cong-zhu(Department of Obstetrics and Gynaecology,Maternal and Child Health Hospital of Puning,Guangdong,515300;Cancer Hospital of Shantou University Medical College,Shantou,Guangdong)

机构地区：[1]广东省普宁市妇幼保健院妇产科,515300 [2]汕头大学医学院附属肿瘤医院

出　　处：《岭南急诊医学杂志》2022年第2期134-136,共3页Lingnan Journal of Emergency Medicine

摘　　要：目的:探究接受手术治疗的早期宫颈癌患者的临床特征及预后随时间的变化趋势。方法:回顾性纳入广东汕头地区某三甲医院2006-2020年期间接受手术治疗的早期宫颈癌(FIGO 2009宫颈癌分期I A-I B1期)患者,比较不同时间段患者的临床特征与预后。结果:共有1134例于2006-2020年期间接受手术治疗的早期宫颈癌患者纳入分析,其中患者例数有随时间逐渐上升的趋势(2006-2010年292例,2011-2015年368例,2016-2020年474例)。在所分析的临床特征中,平均年龄、存在高危因素的比例以及术后接受辅助治疗的比例呈现下降趋势,而组织学类型为腺癌、临床分期为I A1期、以腹腔镜作为手术入路、手术类型为C型(即经典的广泛性子宫切除术)的比例则由上升趋势,但患者的平均体重质量指数以及存在高危因素的比例则无显著差异。在预后上,术后1年死亡率未见显著改变(分别为2.4%、1.9%以及3.4%,P=0.398)。结论:2006-2020年期间广东汕头地区接受手术治疗的早期宫颈癌患者在某些临床特征呈现特征性改变,预后总体良好但无显著变化。Objective:To investigate the trends in clinical characteristics and prognosis of patients with early cervical cancer undergoing surgical treatment. Methods:Patients with early cervical cancer(FIGO 2009 cervical cancer stage I A to I B1 stage)who received surgical treatment from a tertiary hospital in Shantou,Guangdong Province from2006 to 2020 were retrospectively included. Several clinical characteristics and prognosis were compared between patients diagnosed at different time. Results:A total of 1134 patients with early cervical cancer who underwent surgical treatment during 2006-2020 were included in the analysis,and there was a trend of increasing number of patients(292cases in 2006-2010,368 in 2011-2015,and 474 in 2016-2020). Among the investigated clinical features,the mean age,the proportion of comorbid high-risk factors,and the proportion of postoperative adjuvant therapy showed a downward trend,while the proportions of adenocarcinoma as the histological type,stage I A1,laparoscopy,and receivingtype C radical hysterectomy increased,but there was no significant difference in the mean body mass index and the proportion of patients with high-risk factors. In terms of prognosis,1-year mortality did not change significantly(2.4%,1.9%,and 3.4%,respectively,P=0.398). Conclusion:During 2006-2020,patients with early cervical cancer who received surgical treatment in Shantou,Guangdong showed featured changes in some clinical characteristics,and the prognosis was acceptable but did not change significantly.

关 键 词：宫颈癌 预后 时间趋势 

分 类 号：R737.33[医药卫生—肿瘤]