幽门螺杆菌感染与焦虑及生活质量相关性的研究  

Correlation research on Helicobacter pylori infection with anxiety and quality of life

作　　者：韩宇豪 彭琼[1] Han Yuhao;Peng Qiong(Department of Gastroenterology Hefei First People's Group Hospital,Hefei 230001,China)

机构地区：[1]合肥市第一人民医院消化内科,安徽合肥230001

出　　处：《江苏科技信息》2022年第9期75-80,共6页Jiangsu Science and Technology Information

摘　　要：为了调查研究健康人群的幽门螺杆菌(Hp)感染情况及与焦虑、生活质量的相关影响,文章分析了2020年10月至2021年6月在合肥市第一人民医院行14C-尿素呼气试验(14C-Urea Breath Test,14C-UBT)健康体检人群共161例的一般资料,分为幽门螺杆菌感染阳性及感染阴性两组,分别采用汉密尔顿焦虑量表(Hamilton Anxiety Scale,HAMA)和健康调查简表(SF-36简表)进行评分并比较两组间的差异。结果显示:Hp阳性组中吸烟者占比较阴性组高,差异有统计学意义(P<0.05)。Hp感染阳性组平均HAMA评分较阴性组高,差异有统计学意义(P<0.05)。Hp感染阳性组较阴性组的SF-36评分得分有明显降低,两组之间差异有统计学意义(P均<0.05)。Hp感染与吸烟、焦虑程度均呈正相关,与生活质量均呈负相关(P均<0.05)。吸烟(OR为4.40,95%CI 1.33~14.52,P=0.015)、焦虑程度(OR为1.49,95%CI 1.27~1.75,P<0.001)、一般健康状况(OR为0.96,95%CI 0.93~0.99,P=0.006)是Hp感染的独立危险因素。Hp感染与焦虑状态存在明显正相关性。Hp感染后,生活质量有所下降。吸烟者、焦虑患者、一般健康状况低下者的Hp感染风险较高。To investigate the Helicobacter pylori(Hp)infection in healthy people and its related effects on anxiety and quality of life,the general data of a total of 161 healthy people undergoing a 14C-Urea Breath Test(14C-UBT)in Hefei First People’s Group Hospital from October 2020 to June 2021 was analysed in this paper.They were divided into positive and negative H.pylori infections.The two groups with negative infections were scored using the Hamilton Anxiety Scale(HAMA)and the Health Survey Brief(SF-36 Brief)respectively,and the differences between the two groups were compared.The percentage of smokers in the Hp positive group was higher than that in the negative group,and the difference was statistically significant(P<0.05).The average HAMA score of the Hp infection positive group was higher than that of the negative group,and the difference was statistically significant(P<0.05).The SF-36 score of the Hp infection positive group was significantly lower than that of the negative group,and the difference between the two groups was statistically significant(all P<0.05).Hp infection is positively correlated with smoking and anxiety,and negatively correlated with quality of life(all P<0.05).Smoking(OR 4.40,95%CI 1.33-14.52,P=0.015),anxiety level(OR 1.49,95%CI 1.27-1.75,P<0.001),general health status(OR 0.96,95%CI 0.93-0.99,P=0.006)is an independent risk factor for Hp infection.There is a significant positive correlation between Hp infection and anxiety.After Hp infection,the quality of life has declined.Smokers,anxious patients and people with poor general health have a higher risk of Hp infection.

关 键 词：幽门螺杆菌 焦虑 SF-36 

分 类 号：R57[医药卫生—消化系统]