Assessment of resting energy expenditure in patients with cirrhosis  

作　　者：Shaiane Ferreira Cláudio Augusto Marroni Jessica Taina Stein Roberta Rayn Ana Cristhina Henz Natália P Schmidt Randhall B Carteri Sabrina Alves Fernandes 

机构地区：[1]Postgraduate Program in Hepatology,Federal University of Health Sciences of Porto Alegre(UFCSPA),Porto Alegre 90050-170,Brazil [2]Department of Nutrition,Centro Universitário Metodista-IPA,Porto Alegre 90420-060,Brazil [3]Department of Health and Behavior,Catholic University of Pelotas,Pelotas 96015-560,Brazil

出　　处：《World Journal of Hepatology》2022年第4期802-811,共10页世界肝病学杂志（英文版）（电子版）

摘　　要：BACKGROUND Malnutrition affects 20%to 50%of patients with cirrhosis.It may be associated with serious complications and has a direct impact on prognosis.Resting energy expenditure(REE)is an important parameter to guide the optimization of therapy and recovery of nutritional status in patients with cirrhosis.However,the REE of patients with cirrhosis is still unclear,casting doubt upon the optimal nutritional management approach.AIM To identify the best method that predicts the REE of cirrhotic patients,using indirect calorimetry(IC)as the gold standard.METHODS An observational study was performed on 90 patients with cirrhosis.REE was assessed by IC,bioelectrical impedance analysis(BIA),and predictive formulas,which were compared using Bland-Altman plots and the Student’s t-test.RESULTS REE values measured by IC(1607.72±257.4 kcal)differed significantly from those determined by all other methods(BIA:1790.48±352.1 kcal;Harris&Benedict equation:2373.54±254.9 kcal;IOM equation:1648.95±185.6 kcal;Cunningham equation:1764.29±246.2 kcal),except the Food and Agriculture Organization of the United Nations,World Health Organization,and United Nations University(FAO/WHO/UNU)(1616.07±214.6 kcal)and McArdle(1611.30±241.8 kcal)equations.We found no significant association when comparing IC and 24-h dietary recall among different Child-Pugh classes of cirrhosis.CONCLUSION The IOM and FAO/WHO/UNU equations have the best agreement with the CI.These results indicate a possibility of different tools for the clinical practice on cirrhotic patients.

关 键 词：Liver cirrhosis CALORIMETRY Indirect Energy metabolism MALNUTRITION 

分 类 号：R575.2[医药卫生—消化系统]