Answer:vascular changes in age-related macular degeneration  

作　　者：Alessandro Arrigo Maurizio Battaglia Parodi Francesco Bandello 

机构地区：[1]Department of Ophthalmology,Scientific Institute San Raffaele,Vita-Salute University,Milan,Italy

出　　处：《Annals of Eye Science》2019年第1期87-88,共2页眼科学年鉴（英文）

摘　　要：We were very pleased by the paper of Borrelli and colleagues(1)and we would thank for their consideration.Nowadays,macular diseases,such as age-related macular degeneration(AMD)underwent a strong improvement in terms of pathophysiology understanding and treatments efficacy monitoring,thank to multimodal imaging techniques.These methodologies are reliable,feasible,easily reproducible,and provide very detailed microstructural information regarding retinal status in a non invasively way.Their introduction in clinical practice opened new frontiers for the ophthalmologists to face macular diseases.One of the most recently introduced technique is optical coherence tomography angiography(OCTA),which offered for the first time the opportunity to study in detail the retinal vascular network without the adoption of dye.Although multimodal imaging is mainly analyzed from the qualitative point of view,in the last years even more advanced quantitative approaches were introduced to further improve the amount of information reached by images analyses.In the context of OCTA,vessel density still represents the most used measure;it provides useful information regarding vascular deficits occurring in macular diseases(2).However,vessel density reductions resulted not pathognomonic of given retinal diseases.

关 键 词：DEGENERATION THANK qualitative 

分 类 号：TP3[自动化与计算机技术—计算机科学与技术]